The contribution of mass spectrometry to the biosciences

Simon J. Gaskell

Research output: Contribution to journalArticlepeer-review

Abstract

This paper provides a personal perspective on the recent development of mass spectrometry, arguing that these developments are increasingly driven by the research demands of the life sciences. Within that context, the analytical requirements of proteomics (the determination of the protein constituents of a cell or organism) provide useful examples of the need for very high sensitivity, selectivity to match the required analytical outcomes, rigorous quantification (both relative and absolute) of individual components, and quantitative definition of cellular processes. © 2006 Elsevier B.V. All rights reserved.
Original languageEnglish
Pages (from-to)6404-6408
Number of pages4
JournalApplied Surface Science
Volume252
Issue number19
DOIs
Publication statusPublished - 30 Jul 2006

Keywords

  • Mass spectrometry
  • Peptides
  • Post-genome science
  • Proteins
  • Proteomics

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