The design of efficient and selective routes to pyridyl analogues of 3-oxo-3,4-dihydro-2H-1,4-(benzothiazine or benzoxazine)-6-carbaldehydes

G Brooks, S Dabbs, D T Davies, A J Hennessy, G E Jones, R E Markwell, T J Miles, N A Owston, N D Pearson, T W Peng

Research output: Contribution to journalArticlepeer-review

Abstract

This Letter describes the synthesis of challenging pyridyl analogues of 3-oxo-3,4-dihydro-2H-1,4-(benzothiazine or benzoxazine)-6-carbaldehydes. The six different routes described are high yielding, contain no major purification issues and have been used to give gram quantities of each aldehyde. (C) 2010 Elsevier Ltd. All rights reserved.
Original languageEnglish
Pages (from-to)5035-5037
Number of pages3
JournalTetrahedron Letters
Volume51
Issue number38
DOIs
Publication statusPublished - 2010

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