The dominant cold-sensitive Out-cold mutants of Drosophila melanogaster have novel missense mutations in the voltage-gated sodium channel gene paralytic

Helen A. Lindsay; Richard Baines; Richard Ffrench-Constant; Kathryn Lilley; Howard T. Jacobs; Kevin M C O'Dell

doi:10.1534/genetics.108.090951

The dominant cold-sensitive Out-cold mutants of Drosophila melanogaster have novel missense mutations in the voltage-gated sodium channel gene paralytic

Helen A. Lindsay, Richard Baines, Richard Ffrench-Constant, Kathryn Lilley, Howard T. Jacobs, Kevin M C O'Dell

Research output: Contribution to journal › Article › peer-review

Abstract

Here we report the molecular characterization of Out-cold (Ocd) mutants of Drosophila melanogaster, which produce a dominant, X-linked, cold-sensitive paralytic phenotype. From its initial 1.5-Mb cytological location within 13F1-16A2, P-element and SNP mapping reduced the Ocd critical region to

Original language	English
Pages (from-to)	873-884
Number of pages	11
Journal	Genetics
Volume	180
Issue number	2
DOIs	https://doi.org/10.1534/genetics.108.090951
Publication status	Published - Oct 2008

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10.1534/genetics.108.090951

http://www.genetics.org/cgi/reprint/180/2/873

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title = "The dominant cold-sensitive Out-cold mutants of Drosophila melanogaster have novel missense mutations in the voltage-gated sodium channel gene paralytic",

abstract = "Here we report the molecular characterization of Out-cold (Ocd) mutants of Drosophila melanogaster, which produce a dominant, X-linked, cold-sensitive paralytic phenotype. From its initial 1.5-Mb cytological location within 13F1-16A2, P-element and SNP mapping reduced the Ocd critical region to",

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AU - Lilley, Kathryn

AU - Jacobs, Howard T.

AU - O'Dell, Kevin M C

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The dominant cold-sensitive Out-cold mutants of Drosophila melanogaster have novel missense mutations in the voltage-gated sodium channel gene paralytic

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