The Ecology and Evolution of Pangenomes

Michael A. Brockhurst; Ellie Harrison; James P.J. Hall; Thomas Richards; Alan McNally; Craig MacLean

doi:10.1016/j.cub.2019.08.012

The Ecology and Evolution of Pangenomes

Michael A. Brockhurst^*, Ellie Harrison, James P.J. Hall, Thomas Richards, Alan McNally, Craig MacLean

^*Corresponding author for this work

Division of Evolution, Infection and Genomics

Research output: Contribution to journal › Review article › peer-review

Abstract

The observation of large differences in gene content when comparing genomes within a species gave rise to the concept of the pangenome. Brockhurst et al. provide an ecological perspective on the evolution of pangenomes, and how their origin and structure derive from the dynamics of horizontal gene transfer.

Original language	English
Pages (from-to)	R1094-R1103
Journal	Current Biology
Volume	29
Issue number	20
DOIs	https://doi.org/10.1016/j.cub.2019.08.012
Publication status	Published - 21 Oct 2019

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http://eprints.whiterose.ac.uk/149533/

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title = "The Ecology and Evolution of Pangenomes",

abstract = "The observation of large differences in gene content when comparing genomes within a species gave rise to the concept of the pangenome. Brockhurst et al. provide an ecological perspective on the evolution of pangenomes, and how their origin and structure derive from the dynamics of horizontal gene transfer.",

author = "Brockhurst, {Michael A.} and Ellie Harrison and Hall, {James P.J.} and Thomas Richards and Alan McNally and Craig MacLean",

year = "2019",

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AU - Brockhurst, Michael A.

AU - Harrison, Ellie

AU - Hall, James P.J.

AU - Richards, Thomas

AU - McNally, Alan

AU - MacLean, Craig

PY - 2019/10/21

Y1 - 2019/10/21

N2 - The observation of large differences in gene content when comparing genomes within a species gave rise to the concept of the pangenome. Brockhurst et al. provide an ecological perspective on the evolution of pangenomes, and how their origin and structure derive from the dynamics of horizontal gene transfer.

AB - The observation of large differences in gene content when comparing genomes within a species gave rise to the concept of the pangenome. Brockhurst et al. provide an ecological perspective on the evolution of pangenomes, and how their origin and structure derive from the dynamics of horizontal gene transfer.

U2 - 10.1016/j.cub.2019.08.012

DO - 10.1016/j.cub.2019.08.012

M3 - Review article

C2 - 31639358

AN - SCOPUS:85073435031

SN - 0960-9822

VL - 29

SP - R1094-R1103

JO - Current Biology

JF - Current Biology

IS - 20

ER -

The Ecology and Evolution of Pangenomes

Abstract

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