The solubilisation of griseofulvin in 1 wt% aqueous micellar solutions of Pluronic F127 at 37 °C has been modified by adding polyethylene glycol PEG 35000 or poly(vinylpyrrolidone) PVP K30. The solubilisation capacity expressed in terms of unit weight of F127 is increased by the addition of 0.5 wt% PEG 35000 to a value approaching double that of a 2.5 wt% solution of F127 alone, but there is no advantage in adding 0.5 wt% PVP K30. © 2011 Elsevier B.V. All rights reserved.
|Number of pages||2|
|Journal||International Journal of Pharmaceutics|
|Publication status||Published - 16 May 2011|
- Pluronic F127
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Organic Materials Innovation Centre (OMIC)
Michael Turner (Participant), Stephen Yeates (Participant), Colin Booth (Participant), Iain May (Participant), David Collison (Participant), David Procter (Participant) & Andromachi Malandraki (Participant)
Impact: Technological, Economic, Society and culture