The effect of ultraviolet B-induced vitamin D levels on host resistance to Mycobacterium tuberculosis: A pilot study in immigrant Asian adults living in the United Kingdom

Paul Devakar Yesudian; Jacqueline Lesley Berry; Siouxsie Wiles; Stefan Hoyle; Douglas Brownlie Young; Ann Katarina Haylett; Lesley Elizabeth Rhodes; Peter Davies

doi:10.1111/j.1600-0781.2008.00339.x

The effect of ultraviolet B-induced vitamin D levels on host resistance to Mycobacterium tuberculosis: A pilot study in immigrant Asian adults living in the United Kingdom

Paul Devakar Yesudian, Jacqueline Lesley Berry, Siouxsie Wiles, Stefan Hoyle, Douglas Brownlie Young, Ann Katarina Haylett, Lesley Elizabeth Rhodes, Peter Davies

Research output: Contribution to journal › Article › peer-review

Abstract

Asian immigrants to the United Kingdom demonstrate much higher tuberculosis rates than the indigenous population. This is postulated to be because of their low vitamin D levels, consequent upon a combination of diet and their reduced ultraviolet (UV) exposure in the United Kingdom, because vitamin D enhances antimycobacterial activity in in vitro systems. The aim of this study was to examine the relationship between UVB exposure, vitamin D levels and tuberculo-immunity in Asian immigrants in the United Kingdom. Suberythemal UVB treatments were given to eight subjects on 3 consecutive days, using broadband UVB fluorescent lamps. Blood was sampled for 25-hydroxyvitamin D (25-OH D) and whole blood functional assays were performed for antimycobacterial immunity. The mean 25-OH D level increased from a baseline of 11.23 ng/ml (95% CI 6.7-20.39) to 20.39 ng/ml (95% CI 16.6-20) following UVB treatment, P

Original language	English
Pages (from-to)	97-98
Number of pages	1
Journal	Photodermatology Photoimmunology and Photomedicine
Volume	24
Issue number	2
DOIs	https://doi.org/10.1111/j.1600-0781.2008.00339.x
Publication status	Published - Apr 2008

Keywords

Tuberculosis
Ultraviolet B
Vitamin D

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/j.1600-0781.2008.00339.x

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Yesudian, P. D., Berry, J. L., Wiles, S., Hoyle, S., Young, D. B., Haylett, A. K., Rhodes, L. E., & Davies, P. (2008). The effect of ultraviolet B-induced vitamin D levels on host resistance to Mycobacterium tuberculosis: A pilot study in immigrant Asian adults living in the United Kingdom. Photodermatology Photoimmunology and Photomedicine, 24(2), 97-98. https://doi.org/10.1111/j.1600-0781.2008.00339.x

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title = "The effect of ultraviolet B-induced vitamin D levels on host resistance to Mycobacterium tuberculosis: A pilot study in immigrant Asian adults living in the United Kingdom",

abstract = "Asian immigrants to the United Kingdom demonstrate much higher tuberculosis rates than the indigenous population. This is postulated to be because of their low vitamin D levels, consequent upon a combination of diet and their reduced ultraviolet (UV) exposure in the United Kingdom, because vitamin D enhances antimycobacterial activity in in vitro systems. The aim of this study was to examine the relationship between UVB exposure, vitamin D levels and tuberculo-immunity in Asian immigrants in the United Kingdom. Suberythemal UVB treatments were given to eight subjects on 3 consecutive days, using broadband UVB fluorescent lamps. Blood was sampled for 25-hydroxyvitamin D (25-OH D) and whole blood functional assays were performed for antimycobacterial immunity. The mean 25-OH D level increased from a baseline of 11.23 ng/ml (95% CI 6.7-20.39) to 20.39 ng/ml (95% CI 16.6-20) following UVB treatment, P",

keywords = "Tuberculosis, Ultraviolet B, Vitamin D",

author = "Yesudian, {Paul Devakar} and Berry, {Jacqueline Lesley} and Siouxsie Wiles and Stefan Hoyle and Young, {Douglas Brownlie} and Haylett, {Ann Katarina} and Rhodes, {Lesley Elizabeth} and Peter Davies",

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doi = "10.1111/j.1600-0781.2008.00339.x",

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Yesudian, PD, Berry, JL, Wiles, S, Hoyle, S, Young, DB, Haylett, AK, Rhodes, LE & Davies, P 2008, 'The effect of ultraviolet B-induced vitamin D levels on host resistance to Mycobacterium tuberculosis: A pilot study in immigrant Asian adults living in the United Kingdom', Photodermatology Photoimmunology and Photomedicine, vol. 24, no. 2, pp. 97-98. https://doi.org/10.1111/j.1600-0781.2008.00339.x

The effect of ultraviolet B-induced vitamin D levels on host resistance to Mycobacterium tuberculosis: A pilot study in immigrant Asian adults living in the United Kingdom. / Yesudian, Paul Devakar; Berry, Jacqueline Lesley; Wiles, Siouxsie et al.
In: Photodermatology Photoimmunology and Photomedicine, Vol. 24, No. 2, 04.2008, p. 97-98.

Research output: Contribution to journal › Article › peer-review

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T1 - The effect of ultraviolet B-induced vitamin D levels on host resistance to Mycobacterium tuberculosis: A pilot study in immigrant Asian adults living in the United Kingdom

AU - Yesudian, Paul Devakar

AU - Berry, Jacqueline Lesley

AU - Wiles, Siouxsie

AU - Hoyle, Stefan

AU - Young, Douglas Brownlie

AU - Haylett, Ann Katarina

AU - Rhodes, Lesley Elizabeth

AU - Davies, Peter

PY - 2008/4

Y1 - 2008/4

N2 - Asian immigrants to the United Kingdom demonstrate much higher tuberculosis rates than the indigenous population. This is postulated to be because of their low vitamin D levels, consequent upon a combination of diet and their reduced ultraviolet (UV) exposure in the United Kingdom, because vitamin D enhances antimycobacterial activity in in vitro systems. The aim of this study was to examine the relationship between UVB exposure, vitamin D levels and tuberculo-immunity in Asian immigrants in the United Kingdom. Suberythemal UVB treatments were given to eight subjects on 3 consecutive days, using broadband UVB fluorescent lamps. Blood was sampled for 25-hydroxyvitamin D (25-OH D) and whole blood functional assays were performed for antimycobacterial immunity. The mean 25-OH D level increased from a baseline of 11.23 ng/ml (95% CI 6.7-20.39) to 20.39 ng/ml (95% CI 16.6-20) following UVB treatment, P

AB - Asian immigrants to the United Kingdom demonstrate much higher tuberculosis rates than the indigenous population. This is postulated to be because of their low vitamin D levels, consequent upon a combination of diet and their reduced ultraviolet (UV) exposure in the United Kingdom, because vitamin D enhances antimycobacterial activity in in vitro systems. The aim of this study was to examine the relationship between UVB exposure, vitamin D levels and tuberculo-immunity in Asian immigrants in the United Kingdom. Suberythemal UVB treatments were given to eight subjects on 3 consecutive days, using broadband UVB fluorescent lamps. Blood was sampled for 25-hydroxyvitamin D (25-OH D) and whole blood functional assays were performed for antimycobacterial immunity. The mean 25-OH D level increased from a baseline of 11.23 ng/ml (95% CI 6.7-20.39) to 20.39 ng/ml (95% CI 16.6-20) following UVB treatment, P

KW - Tuberculosis

KW - Ultraviolet B

KW - Vitamin D

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DO - 10.1111/j.1600-0781.2008.00339.x

M3 - Article

SN - 1600-0781

VL - 24

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JO - Photodermatology Photoimmunology and Photomedicine

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IS - 2

ER -

The effect of ultraviolet B-induced vitamin D levels on host resistance to Mycobacterium tuberculosis: A pilot study in immigrant Asian adults living in the United Kingdom

Abstract

Keywords

UN SDGs

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