The effects of beta blockade on dopamine and dobutamine induced hypokalaemia in dogs

Douglas Corfield; M. Smith; H. F. Drake; D. R. Corfield; T. Treasure

doi:10.1007/BF00255601

The effects of beta blockade on dopamine and dobutamine induced hypokalaemia in dogs

Douglas Corfield, M. Smith, H. F. Drake, D. R. Corfield, T. Treasure

Research output: Contribution to journal › Article › peer-review

Abstract

The effect of beta1 and beta2 blockade on dopamine and dobutamine induced hypokalaemia was investigated in dogs. Arterial plasma potassium was continuously monitored using a potassium-sensitive electrode sited in the abdominal aorta. Dopamine and dobutamine were infused at 15μg kg-1 min-1 into animals pre-treated with atenolol (0.5 mg kg-1) or ICI 118551 (0.5 mg kg-1) and the potassium changes compared to those seen in control animals. The inotrope infusions caused a small and transient rise in plasma potassium (p

Original language	English
Pages (from-to)	452-457
Number of pages	5
Journal	Intensive care medicine
Volume	15
Issue number	7
DOIs	https://doi.org/10.1007/BF00255601
Publication status	Published - Nov 1989

Keywords

Beta blockade
Dobutamine
Dopamine
Potassium

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10.1007/BF00255601

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title = "The effects of beta blockade on dopamine and dobutamine induced hypokalaemia in dogs",

abstract = "The effect of beta1 and beta2 blockade on dopamine and dobutamine induced hypokalaemia was investigated in dogs. Arterial plasma potassium was continuously monitored using a potassium-sensitive electrode sited in the abdominal aorta. Dopamine and dobutamine were infused at 15μg kg-1 min-1 into animals pre-treated with atenolol (0.5 mg kg-1) or ICI 118551 (0.5 mg kg-1) and the potassium changes compared to those seen in control animals. The inotrope infusions caused a small and transient rise in plasma potassium (p",

keywords = "Beta blockade, Dobutamine, Dopamine, Potassium",

author = "Douglas Corfield and M. Smith and Drake, {H. F.} and Corfield, {D. R.} and T. Treasure",

year = "1989",

month = nov,

doi = "10.1007/BF00255601",

language = "English",

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journal = "Intensive care medicine",

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T1 - The effects of beta blockade on dopamine and dobutamine induced hypokalaemia in dogs

AU - Corfield, Douglas

AU - Smith, M.

AU - Drake, H. F.

AU - Corfield, D. R.

AU - Treasure, T.

PY - 1989/11

Y1 - 1989/11

N2 - The effect of beta1 and beta2 blockade on dopamine and dobutamine induced hypokalaemia was investigated in dogs. Arterial plasma potassium was continuously monitored using a potassium-sensitive electrode sited in the abdominal aorta. Dopamine and dobutamine were infused at 15μg kg-1 min-1 into animals pre-treated with atenolol (0.5 mg kg-1) or ICI 118551 (0.5 mg kg-1) and the potassium changes compared to those seen in control animals. The inotrope infusions caused a small and transient rise in plasma potassium (p

AB - The effect of beta1 and beta2 blockade on dopamine and dobutamine induced hypokalaemia was investigated in dogs. Arterial plasma potassium was continuously monitored using a potassium-sensitive electrode sited in the abdominal aorta. Dopamine and dobutamine were infused at 15μg kg-1 min-1 into animals pre-treated with atenolol (0.5 mg kg-1) or ICI 118551 (0.5 mg kg-1) and the potassium changes compared to those seen in control animals. The inotrope infusions caused a small and transient rise in plasma potassium (p

KW - Beta blockade

KW - Dobutamine

KW - Dopamine

KW - Potassium

U2 - 10.1007/BF00255601

DO - 10.1007/BF00255601

M3 - Article

C2 - 2600289

SN - 1432-1238

VL - 15

SP - 452

EP - 457

JO - Intensive care medicine

JF - Intensive care medicine

IS - 7

ER -

The effects of beta blockade on dopamine and dobutamine induced hypokalaemia in dogs

Abstract

Keywords

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