The EXACT description of biomedical protocols

Larisa N. Soldatova, Wayne Aubrey, Ross D. King, Amanda Clare

    Research output: Contribution to journalArticlepeer-review

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    Abstract

    Motivation: Many published manuscripts contain experiment protocols which are poorly described or deficient in information. This means that the published results are very hard or impossible to repeat. This problem is being made worse by the increasing complexity of high-throughput/automated methods. There is therefore a growing need to represent experiment protocols in an efficient and unambiguous way. Results: We have developed the Experiment ACTions (EXACT) ontology as the basis of a method of representing biological laboratory protocols. We provide example protocols that have been formalized using EXACT, and demonstrate the advantages and opportunities created by using this formalization. We argue that the use of EXACT will result in the publication of protocols with increased clarity and usefulness to the scientific community. © 2008 The Author(s).
    Original languageEnglish
    Pages (from-to)295-303
    Number of pages8
    JournalBioinformatics
    Volume24
    Issue number13
    DOIs
    Publication statusPublished - Jul 2008

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