The existence of geographical clusters of cases of inflammatory polyarthritis in a primary care based register

Alan Silman, Beverley Harrison, Elizabeth Barrett, Deborah Symmons

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Objectives - To determine whether there is any evidence that there are spatial clusters of rheumatoid arthritis in particulars and inflammatory arthritis in general. Methods - Setting was a population based incidence register of inflammatory arthritis: the Norfolk Arthritis Register (NOAR). All cases identified between 1990-1995 were mapped to place of residence. Statistical evidence of clustering was determined by calculating Poisson probabilities in putative areas. Results - Three clusters were identified including one small area (population 85) where five unrelated cases developed during this time period. There was no obvious greater disease homogeneity within clusters and no common environmental factors were identified. Conclusion - Rare clusters of inflammatory polyarthritis do occur. Their significance and cause remain to be elucidated.
    Original languageEnglish
    Pages (from-to)152-154
    Number of pages2
    JournalAnnals of the rheumatic diseases
    Volume59
    Issue number2
    DOIs
    Publication statusPublished - 2000

    Keywords

    • Space-Time Clustering
    • Cretaceous

    Fingerprint

    Dive into the research topics of 'The existence of geographical clusters of cases of inflammatory polyarthritis in a primary care based register'. Together they form a unique fingerprint.

    Cite this