The genetics of juvenile idiopathic arthritis: Current understanding and future prospects

Joanna E. Cobb; Anne Hinks; Wendy Thomson

doi:10.1093/rheumatology/ket314

The genetics of juvenile idiopathic arthritis: Current understanding and future prospects

Joanna E. Cobb, Anne Hinks, Wendy Thomson

Research output: Contribution to journal › Article › peer-review

Abstract

Understanding the genetic risk of JIA, a relatively rare chronic disease, is a challenging task, but recent research in this field has shown great advances. This review summarizes the current understanding of the genetic architecture of JIA susceptibility and proposes where this work is heading in the coming years. Insights into how we might progress this relatively understudied field will be provided, highlighting how the field will move towards the ultimate goals of predicting long-term disease outcomes at onset, predicting drug response, and move towards more targeted treatment options for children with JIA. © The Author 2013. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved.

Original language	English
Article number	ket314
Pages (from-to)	592-599
Number of pages	7
Journal	Rheumatology
Volume	53
Issue number	4
Early online date	18 Sept 2013
DOIs	https://doi.org/10.1093/rheumatology/ket314
Publication status	Published - Apr 2014

Keywords

Autoimmune disease
Genetics
Juvenile idiopathic arthritis
Predicting drug response

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KW - Genetics

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The genetics of juvenile idiopathic arthritis: Current understanding and future prospects

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