The genetics of juvenile idiopathic arthritis: Current understanding and future prospects

Joanna E. Cobb, Anne Hinks, Wendy Thomson

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Understanding the genetic risk of JIA, a relatively rare chronic disease, is a challenging task, but recent research in this field has shown great advances. This review summarizes the current understanding of the genetic architecture of JIA susceptibility and proposes where this work is heading in the coming years. Insights into how we might progress this relatively understudied field will be provided, highlighting how the field will move towards the ultimate goals of predicting long-term disease outcomes at onset, predicting drug response, and move towards more targeted treatment options for children with JIA. © The Author 2013. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved.
    Original languageEnglish
    Article numberket314
    Pages (from-to)592-599
    Number of pages7
    JournalRheumatology
    Volume53
    Issue number4
    Early online date18 Sep 2013
    DOIs
    Publication statusPublished - Apr 2014

    Keywords

    • Autoimmune disease
    • Genetics
    • Juvenile idiopathic arthritis
    • Predicting drug response

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