The genomic approach to growth prediction

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Background: A major objective when using recombinant human growth hormone (rhGH) in childhood is to attain the maximum sustained growth response that can be achieved in an individual child while avoiding adverse events and ensuring that biomarkers of response, such as insulin-like growth factor I (IGF-I), remain within acceptable limits. Conclusion: In practice, this is currently achieved by titrating GH dose against growth rate and serum IGF-I concentration.

    Original languageEnglish
    Pages (from-to)10-15
    Number of pages6
    JournalHormone Research
    Volume67
    Issue numberSUPPL. 1
    DOIs
    Publication statusPublished - Feb 2007

    Keywords

    • Growth hormone deficiency
    • Growth hormone receptor
    • Insulin-like growth factor I
    • Small-for-gestational age
    • Turner syndrome

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