TY - JOUR
T1 - The impact of atmospheric pollution on vitamin D status of infants and toddlers in Delhi, India
AU - Agarwal, K. S.
AU - Puliyel, J. M.
AU - Mughal, M. Z.
AU - Upadhyay, P.
AU - Berry, J. L.
AU - Mawer, E. B.
PY - 2002
Y1 - 2002
N2 - Aims: To compare the vitamin D status of 34 children, 9-24 months old, living in an area of Delhi renowned for high levels of atmospheric pollution (Mori Gate), with a comparable age matched group of children from a less polluted (Gurgaon) area of the city. Methods: Serum concentrations of calcium, alkaline phosphatase (ALP), parathyroid hormone (PTH), 25-hydroxyvitamin D (25(OH)D), and 1,25-dihydroxyvitamin D (1,25(OH)2D) were measured. Haze scores, regarded as a surrogate marker of solar UVB radiation reaching ground level, were measurec in both areas. Results: Mean 25(OH)D of children in the Mori Gate area was 12.4 (7) ng/ml, compared with 27.1 (7) ng/ml in children living in the Gurgaon area (p <0.001). The median ALP (p <0.05) and mear PTH (p <0.001) concentrations were higher in children living in the Mori Gate area than in the Gurgaon area. The mean haze score in the Mori Gate area (2.1 (0.5)) was significantly lower (p <0.05 than in the Gurgaon area (2.7 (0.4)), indicating less solar UVB reaching the ground in Mori Gate. Conclusion: We suggest that children living in areas of high atmospheric pollution are at risk of developing vitamin D deficiency rickets and should be offered vitamin D supplements.
AB - Aims: To compare the vitamin D status of 34 children, 9-24 months old, living in an area of Delhi renowned for high levels of atmospheric pollution (Mori Gate), with a comparable age matched group of children from a less polluted (Gurgaon) area of the city. Methods: Serum concentrations of calcium, alkaline phosphatase (ALP), parathyroid hormone (PTH), 25-hydroxyvitamin D (25(OH)D), and 1,25-dihydroxyvitamin D (1,25(OH)2D) were measured. Haze scores, regarded as a surrogate marker of solar UVB radiation reaching ground level, were measurec in both areas. Results: Mean 25(OH)D of children in the Mori Gate area was 12.4 (7) ng/ml, compared with 27.1 (7) ng/ml in children living in the Gurgaon area (p <0.001). The median ALP (p <0.05) and mear PTH (p <0.001) concentrations were higher in children living in the Mori Gate area than in the Gurgaon area. The mean haze score in the Mori Gate area (2.1 (0.5)) was significantly lower (p <0.05 than in the Gurgaon area (2.7 (0.4)), indicating less solar UVB reaching the ground in Mori Gate. Conclusion: We suggest that children living in areas of high atmospheric pollution are at risk of developing vitamin D deficiency rickets and should be offered vitamin D supplements.
U2 - 10.1136/adc.87.2.111
DO - 10.1136/adc.87.2.111
M3 - Article
SN - 0003-9888
VL - 87
SP - 111
EP - 113
JO - Archives of Disease in Childhood
JF - Archives of Disease in Childhood
IS - 2
ER -
