The impact of intrinsic ageing on the protein composition of the dermal-epidermal junction.

AK Langton; Poonam Halai; CEM Griffiths; Michael J Sherratt; Rachel EB Watson

doi:10.1016/j.mad.2016.03.006

The impact of intrinsic ageing on the protein composition of the dermal-epidermal junction.

Division of Musculoskeletal & Dermatological Sciences (L5)

Research output: Contribution to journal › Article › peer-review

Abstract

The dermal-epidermal junction of human skin exhibits age-related remodelling, resulting in a flattened appearance and reduced surface area. Despite this, a paucity of information is available regarding which protein components change with advancing age. Here we report a significant reduction in the protein distribution of collagen IV (P

Original language	English
Pages (from-to)	14-16
Journal	Mechanisms of ageing and development\|Mech Ageing Dev
Volume	156
DOIs	https://doi.org/10.1016/j.mad.2016.03.006
Publication status	Published - 21 Mar 2016

Keywords

dermal-epidermal junction
intrinsic ageing

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10.1016/j.mad.2016.03.006

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title = "The impact of intrinsic ageing on the protein composition of the dermal-epidermal junction.",

abstract = "The dermal-epidermal junction of human skin exhibits age-related remodelling, resulting in a flattened appearance and reduced surface area. Despite this, a paucity of information is available regarding which protein components change with advancing age. Here we report a significant reduction in the protein distribution of collagen IV (P",

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author = "AK Langton and Poonam Halai and CEM Griffiths and Sherratt, \{Michael J\} and Watson, \{Rachel EB\}",

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AU - Langton, AK

AU - Halai, Poonam

AU - Griffiths, CEM

AU - Sherratt, Michael J

AU - Watson, Rachel EB

PY - 2016/3/21

Y1 - 2016/3/21

N2 - The dermal-epidermal junction of human skin exhibits age-related remodelling, resulting in a flattened appearance and reduced surface area. Despite this, a paucity of information is available regarding which protein components change with advancing age. Here we report a significant reduction in the protein distribution of collagen IV (P

AB - The dermal-epidermal junction of human skin exhibits age-related remodelling, resulting in a flattened appearance and reduced surface area. Despite this, a paucity of information is available regarding which protein components change with advancing age. Here we report a significant reduction in the protein distribution of collagen IV (P

KW - dermal-epidermal junction

KW - intrinsic ageing

U2 - 10.1016/j.mad.2016.03.006

DO - 10.1016/j.mad.2016.03.006

M3 - Article

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SN - 1872-6216

VL - 156

SP - 14

EP - 16

JO - Mechanisms of ageing and development|Mech Ageing Dev

JF - Mechanisms of ageing and development|Mech Ageing Dev

ER -

The impact of intrinsic ageing on the protein composition of the dermal-epidermal junction.

Abstract

Keywords

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