Abstract
Insulin-like growth factor binding protein 3 (IGFBP-3) is the most abundant insulin-like growth factor binding protein in the circulation. The aim of the present work was to investigate the influence of surgery (laparoscopy and open) on the concentration and carbohydrate content of IGFBP-3. The concentration of IGFBP-3 was measured using an immunoradiometric assay (IRMA), its protein profile was characterised using immunoblotting and its sialic acid content was examined by means of Sambucus nigra agglutinin (SNA) affinity chromatography. The concentration of IGFBP-3 was significantly (p
Original language | English |
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Pages (from-to) | 361-369 |
Number of pages | 8 |
Journal | Acta Physiologica Hungarica |
Volume | 93 |
Issue number | 4 |
DOIs | |
Publication status | Published - 2006 |
Keywords
- Insulin-like growth factor binding protein 3
- Laparoscopy
- Open surgery
- Structural modifications