The influence of laparoscopic and open surgery on the concentration and structural modifications of insulin-like growth factor binding protein 3 in the human circulation

Ivona Baricevic-Jones, Ivona Baričević, V. Malenković, D. R. Jones, O. Nedić

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Insulin-like growth factor binding protein 3 (IGFBP-3) is the most abundant insulin-like growth factor binding protein in the circulation. The aim of the present work was to investigate the influence of surgery (laparoscopy and open) on the concentration and carbohydrate content of IGFBP-3. The concentration of IGFBP-3 was measured using an immunoradiometric assay (IRMA), its protein profile was characterised using immunoblotting and its sialic acid content was examined by means of Sambucus nigra agglutinin (SNA) affinity chromatography. The concentration of IGFBP-3 was significantly (p
    Original languageEnglish
    Pages (from-to)361-369
    Number of pages8
    JournalActa Physiologica Hungarica
    Volume93
    Issue number4
    DOIs
    Publication statusPublished - 2006

    Keywords

    • Insulin-like growth factor binding protein 3
    • Laparoscopy
    • Open surgery
    • Structural modifications

    Fingerprint

    Dive into the research topics of 'The influence of laparoscopic and open surgery on the concentration and structural modifications of insulin-like growth factor binding protein 3 in the human circulation'. Together they form a unique fingerprint.

    Cite this