The InterPro database, 2003 brings increased coverage and new features

Nicola J. Mulder; Rolf Apweiler; Teresa K. Attwood; Amos Bairoch; Daniel Barrell; Alex Bateman; David Binns; Margaret Biswas; Paul Bradley; Peer Bork; Phillip Bucher; Richard R. Copley; Emmanuel Courcelle; Ujjwal Das; Richard Durbin; Laurent Falquet; Wolfgang Fleischmann; Sam Griffiths-Jones; Daniel Haft; Nicola Harte; Nicolas Hulo; Daniel Kahn; Alexander Kanapin; Maria Krestyaninova; Rodrigo Lopez; Ivica Letunic; David Lonsdale; Ville Silventoinen; Sandra E. Orchard; Marco Pagni; David Peyruc; Chris P. Ponting; Jeremy D. Selengut; Florence Servant; Christian J A Sigrist; Robert Vaughan; Evgueni M. Zdobnov

doi:10.1093/nar/gkg046

The InterPro database, 2003 brings increased coverage and new features

Nicola J. Mulder, Rolf Apweiler, Teresa K. Attwood, Amos Bairoch, Daniel Barrell, Alex Bateman, David Binns, Margaret Biswas, Paul Bradley, Peer Bork, Phillip Bucher, Richard R. Copley, Emmanuel Courcelle, Ujjwal Das, Richard Durbin, Laurent Falquet, Wolfgang Fleischmann, Sam Griffiths-Jones, Daniel Haft, Nicola HarteNicolas Hulo, Daniel Kahn, Alexander Kanapin, Maria Krestyaninova, Rodrigo Lopez, Ivica Letunic, David Lonsdale, Ville Silventoinen, Sandra E. Orchard, Marco Pagni, David Peyruc, Chris P. Ponting, Jeremy D. Selengut, Florence Servant, Christian J A Sigrist, Robert Vaughan, Evgueni M. Zdobnov

Research output: Contribution to journal › Article › peer-review

Abstract

InterPro, an integrated documentation resource of protein families, domains and functional sites, was created in 1999 as a means of amalgamating the major protein signature databases into one comprehensive resource. PROSITE, Pfam, PRINTS, ProDom, SMART and TIGRFAMs have been manually integrated and curated and are available in InterPro for text- and sequence-based searching. The results are provided in a single format that rationalises the results that would be obtained by searching the member databases individually. The latest release of InterPro contains 5629 entries describing 4280 families, 1239 domains, 95 repeats and 15 posttranslational modifications. Currently, the combined signatures in InterPro cover more than 74% of all proteins in SWISS-PROT and TrEMBL, an increase of nearly 15% since the inception of InterPro. New features of the database include improved searching capabilities and enhanced graphical user interfaces for visualisation of the data. The database is available via a webserver (http://www.ebi.ac.uk/interpro) and anonymous FTP (ftp://ftp.ebi.ac.uk/ pub/databases/interpro).

Original language	English
Pages (from-to)	315-318
Number of pages	3
Journal	Nucleic acids research.
Volume	31
Issue number	1
DOIs	https://doi.org/10.1093/nar/gkg046
Publication status	Published - 1 Jan 2003

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Mulder, N. J., Apweiler, R., Attwood, T. K., Bairoch, A., Barrell, D., Bateman, A., Binns, D., Biswas, M., Bradley, P., Bork, P., Bucher, P., Copley, R. R., Courcelle, E., Das, U., Durbin, R., Falquet, L., Fleischmann, W., Griffiths-Jones, S., Haft, D., ... Zdobnov, E. M. (2003). The InterPro database, 2003 brings increased coverage and new features. Nucleic acids research., 31(1), 315-318. https://doi.org/10.1093/nar/gkg046

@article{7da8d9e2c4ff4eb3a4e721e6e0129814,

title = "The InterPro database, 2003 brings increased coverage and new features",

abstract = "InterPro, an integrated documentation resource of protein families, domains and functional sites, was created in 1999 as a means of amalgamating the major protein signature databases into one comprehensive resource. PROSITE, Pfam, PRINTS, ProDom, SMART and TIGRFAMs have been manually integrated and curated and are available in InterPro for text- and sequence-based searching. The results are provided in a single format that rationalises the results that would be obtained by searching the member databases individually. The latest release of InterPro contains 5629 entries describing 4280 families, 1239 domains, 95 repeats and 15 posttranslational modifications. Currently, the combined signatures in InterPro cover more than 74% of all proteins in SWISS-PROT and TrEMBL, an increase of nearly 15% since the inception of InterPro. New features of the database include improved searching capabilities and enhanced graphical user interfaces for visualisation of the data. The database is available via a webserver (http://www.ebi.ac.uk/interpro) and anonymous FTP (ftp://ftp.ebi.ac.uk/ pub/databases/interpro).",

author = "Mulder, {Nicola J.} and Rolf Apweiler and Attwood, {Teresa K.} and Amos Bairoch and Daniel Barrell and Alex Bateman and David Binns and Margaret Biswas and Paul Bradley and Peer Bork and Phillip Bucher and Copley, {Richard R.} and Emmanuel Courcelle and Ujjwal Das and Richard Durbin and Laurent Falquet and Wolfgang Fleischmann and Sam Griffiths-Jones and Daniel Haft and Nicola Harte and Nicolas Hulo and Daniel Kahn and Alexander Kanapin and Maria Krestyaninova and Rodrigo Lopez and Ivica Letunic and David Lonsdale and Ville Silventoinen and Orchard, {Sandra E.} and Marco Pagni and David Peyruc and Ponting, {Chris P.} and Selengut, {Jeremy D.} and Florence Servant and Sigrist, {Christian J A} and Robert Vaughan and Zdobnov, {Evgueni M.}",

year = "2003",

month = jan,

day = "1",

doi = "10.1093/nar/gkg046",

language = "English",

volume = "31",

pages = "315--318",

journal = "Nucleic acids research.",

issn = "1362-4962",

publisher = "Oxford University Press",

number = "1",

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Mulder, NJ, Apweiler, R, Attwood, TK, Bairoch, A, Barrell, D, Bateman, A, Binns, D, Biswas, M, Bradley, P, Bork, P, Bucher, P, Copley, RR, Courcelle, E, Das, U, Durbin, R, Falquet, L, Fleischmann, W, Griffiths-Jones, S, Haft, D, Harte, N, Hulo, N, Kahn, D, Kanapin, A, Krestyaninova, M, Lopez, R, Letunic, I, Lonsdale, D, Silventoinen, V, Orchard, SE, Pagni, M, Peyruc, D, Ponting, CP, Selengut, JD, Servant, F, Sigrist, CJA, Vaughan, R & Zdobnov, EM 2003, 'The InterPro database, 2003 brings increased coverage and new features', Nucleic acids research., vol. 31, no. 1, pp. 315-318. https://doi.org/10.1093/nar/gkg046

TY - JOUR

T1 - The InterPro database, 2003 brings increased coverage and new features

AU - Mulder, Nicola J.

AU - Apweiler, Rolf

AU - Attwood, Teresa K.

AU - Bairoch, Amos

AU - Barrell, Daniel

AU - Bateman, Alex

AU - Binns, David

AU - Biswas, Margaret

AU - Bradley, Paul

AU - Bork, Peer

AU - Bucher, Phillip

AU - Copley, Richard R.

AU - Courcelle, Emmanuel

AU - Das, Ujjwal

AU - Durbin, Richard

AU - Falquet, Laurent

AU - Fleischmann, Wolfgang

AU - Griffiths-Jones, Sam

AU - Haft, Daniel

AU - Harte, Nicola

AU - Hulo, Nicolas

AU - Kahn, Daniel

AU - Kanapin, Alexander

AU - Krestyaninova, Maria

AU - Lopez, Rodrigo

AU - Letunic, Ivica

AU - Lonsdale, David

AU - Silventoinen, Ville

AU - Orchard, Sandra E.

AU - Pagni, Marco

AU - Peyruc, David

AU - Ponting, Chris P.

AU - Selengut, Jeremy D.

AU - Servant, Florence

AU - Sigrist, Christian J A

AU - Vaughan, Robert

AU - Zdobnov, Evgueni M.

PY - 2003/1/1

Y1 - 2003/1/1

N2 - InterPro, an integrated documentation resource of protein families, domains and functional sites, was created in 1999 as a means of amalgamating the major protein signature databases into one comprehensive resource. PROSITE, Pfam, PRINTS, ProDom, SMART and TIGRFAMs have been manually integrated and curated and are available in InterPro for text- and sequence-based searching. The results are provided in a single format that rationalises the results that would be obtained by searching the member databases individually. The latest release of InterPro contains 5629 entries describing 4280 families, 1239 domains, 95 repeats and 15 posttranslational modifications. Currently, the combined signatures in InterPro cover more than 74% of all proteins in SWISS-PROT and TrEMBL, an increase of nearly 15% since the inception of InterPro. New features of the database include improved searching capabilities and enhanced graphical user interfaces for visualisation of the data. The database is available via a webserver (http://www.ebi.ac.uk/interpro) and anonymous FTP (ftp://ftp.ebi.ac.uk/ pub/databases/interpro).

AB - InterPro, an integrated documentation resource of protein families, domains and functional sites, was created in 1999 as a means of amalgamating the major protein signature databases into one comprehensive resource. PROSITE, Pfam, PRINTS, ProDom, SMART and TIGRFAMs have been manually integrated and curated and are available in InterPro for text- and sequence-based searching. The results are provided in a single format that rationalises the results that would be obtained by searching the member databases individually. The latest release of InterPro contains 5629 entries describing 4280 families, 1239 domains, 95 repeats and 15 posttranslational modifications. Currently, the combined signatures in InterPro cover more than 74% of all proteins in SWISS-PROT and TrEMBL, an increase of nearly 15% since the inception of InterPro. New features of the database include improved searching capabilities and enhanced graphical user interfaces for visualisation of the data. The database is available via a webserver (http://www.ebi.ac.uk/interpro) and anonymous FTP (ftp://ftp.ebi.ac.uk/ pub/databases/interpro).

U2 - 10.1093/nar/gkg046

DO - 10.1093/nar/gkg046

M3 - Article

C2 - 12520011

SN - 1362-4962

VL - 31

SP - 315

EP - 318

JO - Nucleic acids research.

JF - Nucleic acids research.

IS - 1

ER -

The InterPro database, 2003 brings increased coverage and new features

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