The InterPro database, an integrated documentation resource for protein families, domains and functional sites

R. Apweiler; T. K. Attwood; A. Bairoch; A. Bateman; E. Birney; M. Biswas; P. Bucher; L. Cerutti; F. Corpet; M. D R Croning; R. Durbin; L. Falquet; W. Fleischmann; J. Gouzy; H. Hermjakob; N. Hulo; I. Jonassen; D. Kahn; A. Kanapin; Y. Karavidopoulou; R. Lopez; B. Marx; N. J. Mulder; T. M. Oinn; M. Pagni; F. Servant; C. J A Sigrist; E. M. Zdobnov

doi:10.1093/nar/29.1.37

The InterPro database, an integrated documentation resource for protein families, domains and functional sites

R. Apweiler, T. K. Attwood, A. Bairoch, A. Bateman, E. Birney, M. Biswas, P. Bucher, L. Cerutti, F. Corpet, M. D R Croning, R. Durbin, L. Falquet, W. Fleischmann, J. Gouzy, H. Hermjakob, N. Hulo, I. Jonassen, D. Kahn, A. Kanapin, Y. KaravidopoulouR. Lopez, B. Marx, N. J. Mulder, T. M. Oinn, M. Pagni, F. Servant, C. J A Sigrist, E. M. Zdobnov

Research output: Contribution to journal › Article › peer-review

Abstract

Signature database are vital tools for identifying distant relationships in novel sequence and hence for inferring protein function. InterPro is an integrated documentation resource for protein families, domains and functional sites, which amalgamates the efforts of the PROSITE, PRINTS, Pfam and ProDom database projects. Each InterPro entry includes a functional description, annotation, literature references and links back to the relevant member database(s). Release 2.0 of InterPro (October 2000) contains over 3000 entries, representing families, domains, repeats and sites of post-translational modification encoded by a total of 6804 different regular expressions, profiles, fingerprints and Hidden Markov Models. Each InterPro entry lists all the matches against SWISS-PROT and TrEMBL (more than 1 000 000 hits from 462 500 proteins in SWISS-PROT and TrEMBL). The database is accessible for text- and sequence-based searches at http://www.ebi.ac.uk/interpro/. Questions can be emailed to interhelpεbi.ac.uk.

Original language	English
Pages (from-to)	37-40
Number of pages	3
Journal	Nucleic acids research.
Volume	29
Issue number	1
DOIs	https://doi.org/10.1093/nar/29.1.37
Publication status	Published - 1 Jan 2001

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10.1093/nar/29.1.37

PRINTS and InterPro – online resources that facilitate discovery of pharmaceutical and commercially relevant information in proteomic and genomic data-sets
Attwood, T. (Participant), (Participant), (Participant), Croning , M. (Participant), Scordis, P. (Participant), Bradley, P. (Participant), Uddin, A. (Participant), Selley, J. (Participant), (Participant), Moulton , G. (Participant), (Participant) & (Participant)
Impact: Economic, Health and wellbeing, Technological

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Apweiler, R., Attwood, T. K., Bairoch, A., Bateman, A., Birney, E., Biswas, M., Bucher, P., Cerutti, L., Corpet, F., Croning, M. D. R., Durbin, R., Falquet, L., Fleischmann, W., Gouzy, J., Hermjakob, H., Hulo, N., Jonassen, I., Kahn, D., Kanapin, A., ... Zdobnov, E. M. (2001). The InterPro database, an integrated documentation resource for protein families, domains and functional sites. Nucleic acids research., 29(1), 37-40. https://doi.org/10.1093/nar/29.1.37

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title = "The InterPro database, an integrated documentation resource for protein families, domains and functional sites",

abstract = "Signature database are vital tools for identifying distant relationships in novel sequence and hence for inferring protein function. InterPro is an integrated documentation resource for protein families, domains and functional sites, which amalgamates the efforts of the PROSITE, PRINTS, Pfam and ProDom database projects. Each InterPro entry includes a functional description, annotation, literature references and links back to the relevant member database(s). Release 2.0 of InterPro (October 2000) contains over 3000 entries, representing families, domains, repeats and sites of post-translational modification encoded by a total of 6804 different regular expressions, profiles, fingerprints and Hidden Markov Models. Each InterPro entry lists all the matches against SWISS-PROT and TrEMBL (more than 1 000 000 hits from 462 500 proteins in SWISS-PROT and TrEMBL). The database is accessible for text- and sequence-based searches at http://www.ebi.ac.uk/interpro/. Questions can be emailed to interhelpεbi.ac.uk.",

author = "R. Apweiler and Attwood, {T. K.} and A. Bairoch and A. Bateman and E. Birney and M. Biswas and P. Bucher and L. Cerutti and F. Corpet and Croning, {M. D R} and R. Durbin and L. Falquet and W. Fleischmann and J. Gouzy and H. Hermjakob and N. Hulo and I. Jonassen and D. Kahn and A. Kanapin and Y. Karavidopoulou and R. Lopez and B. Marx and Mulder, {N. J.} and Oinn, {T. M.} and M. Pagni and F. Servant and Sigrist, {C. J A} and Zdobnov, {E. M.}",

year = "2001",

month = jan,

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doi = "10.1093/nar/29.1.37",

language = "English",

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Apweiler, R, Attwood, TK, Bairoch, A, Bateman, A, Birney, E, Biswas, M, Bucher, P, Cerutti, L, Corpet, F, Croning, MDR, Durbin, R, Falquet, L, Fleischmann, W, Gouzy, J, Hermjakob, H, Hulo, N, Jonassen, I, Kahn, D, Kanapin, A, Karavidopoulou, Y, Lopez, R, Marx, B, Mulder, NJ, Oinn, TM, Pagni, M, Servant, F, Sigrist, CJA & Zdobnov, EM 2001, 'The InterPro database, an integrated documentation resource for protein families, domains and functional sites', Nucleic acids research., vol. 29, no. 1, pp. 37-40. https://doi.org/10.1093/nar/29.1.37

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T1 - The InterPro database, an integrated documentation resource for protein families, domains and functional sites

AU - Apweiler, R.

AU - Attwood, T. K.

AU - Bairoch, A.

AU - Bateman, A.

AU - Birney, E.

AU - Biswas, M.

AU - Bucher, P.

AU - Cerutti, L.

AU - Corpet, F.

AU - Croning, M. D R

AU - Durbin, R.

AU - Falquet, L.

AU - Fleischmann, W.

AU - Gouzy, J.

AU - Hermjakob, H.

AU - Hulo, N.

AU - Jonassen, I.

AU - Kahn, D.

AU - Kanapin, A.

AU - Karavidopoulou, Y.

AU - Lopez, R.

AU - Marx, B.

AU - Mulder, N. J.

AU - Oinn, T. M.

AU - Pagni, M.

AU - Servant, F.

AU - Sigrist, C. J A

AU - Zdobnov, E. M.

PY - 2001/1/1

Y1 - 2001/1/1

N2 - Signature database are vital tools for identifying distant relationships in novel sequence and hence for inferring protein function. InterPro is an integrated documentation resource for protein families, domains and functional sites, which amalgamates the efforts of the PROSITE, PRINTS, Pfam and ProDom database projects. Each InterPro entry includes a functional description, annotation, literature references and links back to the relevant member database(s). Release 2.0 of InterPro (October 2000) contains over 3000 entries, representing families, domains, repeats and sites of post-translational modification encoded by a total of 6804 different regular expressions, profiles, fingerprints and Hidden Markov Models. Each InterPro entry lists all the matches against SWISS-PROT and TrEMBL (more than 1 000 000 hits from 462 500 proteins in SWISS-PROT and TrEMBL). The database is accessible for text- and sequence-based searches at http://www.ebi.ac.uk/interpro/. Questions can be emailed to interhelpεbi.ac.uk.

AB - Signature database are vital tools for identifying distant relationships in novel sequence and hence for inferring protein function. InterPro is an integrated documentation resource for protein families, domains and functional sites, which amalgamates the efforts of the PROSITE, PRINTS, Pfam and ProDom database projects. Each InterPro entry includes a functional description, annotation, literature references and links back to the relevant member database(s). Release 2.0 of InterPro (October 2000) contains over 3000 entries, representing families, domains, repeats and sites of post-translational modification encoded by a total of 6804 different regular expressions, profiles, fingerprints and Hidden Markov Models. Each InterPro entry lists all the matches against SWISS-PROT and TrEMBL (more than 1 000 000 hits from 462 500 proteins in SWISS-PROT and TrEMBL). The database is accessible for text- and sequence-based searches at http://www.ebi.ac.uk/interpro/. Questions can be emailed to interhelpεbi.ac.uk.

U2 - 10.1093/nar/29.1.37

DO - 10.1093/nar/29.1.37

M3 - Article

C2 - 0011125043

SN - 1362-4962

VL - 29

SP - 37

EP - 40

JO - Nucleic acids research.

JF - Nucleic acids research.

IS - 1

ER -

The InterPro database, an integrated documentation resource for protein families, domains and functional sites

Abstract

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PRINTS and InterPro – online resources that facilitate discovery of pharmaceutical and commercially relevant information in proteomic and genomic data-sets

Cite this