The lithiation of 2-chloroglucal derivatives

Ewan Boyd, Michael R. Hallett, Ray V H Jones, James E. Painter, Prakash Patel, Peter Quayle, Anita J. Waring (née Potts)

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Lithiation of 2-chloroglucal derivatives provides ready access to the corresponding 1-lithioglucals which undergo a variety of serve useful intermediates for further elaboration of the carbohydrate nucleus. Removal of the 2-chloro substituent may be affected using a Birch-type reduction. © 2006 Elsevier Ltd. All rights reserved.
    Original languageEnglish
    Pages (from-to)8337-8341
    Number of pages4
    JournalTetrahedron Letters
    Volume47
    Issue number47
    DOIs
    Publication statusPublished - 20 Nov 2006

    Keywords

    • Glucal
    • Glycal
    • Glycoside
    • Lithiation
    • Metalation
    • Vinyl ether

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