The Magpie Trial: A randomised trial comparing magnesium sulphate with placebo for pre-eclampsia. Outcome for women at 2 years

L. Duley; Barbara Farrell; Nina Armstrong; Patsy Spark; Barbara Roberts; Rebecca Smyth; Mary Tivnan; Anna Laws; Noelene Corfield; Annette Salter; Lisa Thorn; Douglas Altman; Ly Mee Yu; Edgardo Abalos; Berenise Carroli; Lucrecia Dellepiane; Marina Duarte; Hebe Fernandez; Daniel Giordano; Mike Clarke; Alastair Gray; Edmund Hey; James Neilson; Judit Simon; Rory Collins; Anna Karaoglou; Richard Lilford; Stephen Robson; Ian Roberts; Peter Rubin; James Thornton; Sara Twaddle; José Villar; Isabel Walker; Christopher Watkins; Lex Doyle; A. Bimbashi; E. Demalia; O. Gliozheni; A. Shpata; A. Karolinski; M. Lamas; M. Pesaresi; V. Wainer; W. Barbato; M. Paciocco; M. Bertin; E. Boiza; J. Castaldi; Y. Partida; C. Arias; M. Farri; G. Kerz; J. Aguirre; M. De Sagastizábal; R. Falcone; E. Morales; G. Carroli; S. Krupitzky; S. López; M. Palermo; D. Montes Varela; H. Delprato; H. Camusso; M. Curioni; E. Ludmer; R. Brandi; R. Martin; W. Mesas; R. Taralli; M. Lezaola; M. Morosini; E. Andina; L. Bernal; M. Estiú; E. Ulens; B. Ortiz De Speranza; A. Peyrano; M. Damiano; C. Saumench; J. Horn; M. Pritchard; V. Smith-Orr; M. Wilson; A. Lawrence; D. Watson; C. Crowther; J. Paynter; [Unknown] Ashrafunnessa; M. Mannan; M. Shahidullah; L. Shamsuddin; C. Barros Santos; S. Freire; E. Melo; E. Cobo; E. Jaramillo; C. Cardozo; N. Fandiño; H. Gaitán; L. Montaño; J. Lozano; M. Rojas; A. Breto Garcíá; A. Fuentes Ramirez; R. Garcíá Mírás; S. Sampera; U. Farnot; E. Gómez; G. Rojas; R. Valdés; H. Abd El-Kreem; T. Al-Hussaini; E. Hammad; K. Danso; E. Kwapong; E. Ofosu-Barko; M. Padmini Jasper; A. Peedicayil; A. Regi; R. Sharma; A. Chauhan; V. Raut; R. Udani; S. Batra; A. Muthal-Rathore; S. Ramji; V. Zutshi; S. Balakrishnan; E. Eapen; G. Koshy; N. Ambardar; P. Vadakkepat; D. Vaidya; V. Lema; Y. Rijken; E. Tadesse; O. Dada; A. Sofekun; C. Ohiaeri; T. Runsewe-Abiodun; I. Adewole; A. Adeyemo; B. Brown; R. Oladokun; O. Adewale; N. Inimgba; C. John; R. Ogu; B. Ekele; A. Isah; B. Onankpa; R. Jamelle; D. Junejo; N. Ruby Faiz; F. Gul; A. Sherin; K. Bangash; G. Mahmud; K. Masud; N. Tasneem; S. Gassama; A. Soyei; P. Agarwal; V. Rajadurai; N. Pirani; S. Delport; P. Macdonald; R. Mokhondo; R. Pattinson; M. Zondo; M. Adhikari; N. Mnguni; J. Moodley; M. Carstens; G. Kirsten; W. Steyn; J. Van Zyl; A. Helwig; S. L. Jacobson; R. Panosche; E. Hammond; L. Masanganise

doi:10.1111/j.1471-0528.2006.01166.x

The Magpie Trial: A randomised trial comparing magnesium sulphate with placebo for pre-eclampsia. Outcome for women at 2 years

L. Duley, Barbara Farrell, Nina Armstrong, Patsy Spark, Barbara Roberts, Rebecca Smyth, Mary Tivnan, Anna Laws, Noelene Corfield, Annette Salter, Lisa Thorn, Douglas Altman, Ly Mee Yu, Edgardo Abalos, Berenise Carroli, Lucrecia Dellepiane, Marina Duarte, Hebe Fernandez, Daniel Giordano, Mike ClarkeAlastair Gray, Edmund Hey, James Neilson, Judit Simon, Rory Collins, Anna Karaoglou, Richard Lilford, Stephen Robson, Ian Roberts, Peter Rubin, James Thornton, Sara Twaddle, José Villar, Isabel Walker, Christopher Watkins, Lex Doyle, A. Bimbashi, E. Demalia, O. Gliozheni, A. Shpata, A. Karolinski, M. Lamas, M. Pesaresi, V. Wainer, W. Barbato, M. Paciocco, M. Bertin, E. Boiza, J. Castaldi, Y. Partida, C. Arias, M. Farri, G. Kerz, J. Aguirre, M. De Sagastizábal, R. Falcone, E. Morales, G. Carroli, S. Krupitzky, S. López, M. Palermo, D. Montes Varela, H. Delprato, H. Camusso, M. Curioni, E. Ludmer, R. Brandi, R. Martin, W. Mesas, R. Taralli, M. Lezaola, M. Morosini, E. Andina, L. Bernal, M. Estiú, E. Ulens, B. Ortiz De Speranza, A. Peyrano, M. Damiano, C. Saumench, J. Horn, M. Pritchard, V. Smith-Orr, M. Wilson, A. Lawrence, D. Watson, C. Crowther, J. Paynter, [Unknown] Ashrafunnessa, M. Mannan, M. Shahidullah, L. Shamsuddin, C. Barros Santos, S. Freire, E. Melo, E. Cobo, E. Jaramillo, C. Cardozo, N. Fandiño, H. Gaitán, L. Montaño, J. Lozano, M. Rojas, A. Breto Garcíá, A. Fuentes Ramirez, R. Garcíá Mírás, S. Sampera, U. Farnot, E. Gómez, G. Rojas, R. Valdés, H. Abd El-Kreem, T. Al-Hussaini, E. Hammad, K. Danso, E. Kwapong, E. Ofosu-Barko, M. Padmini Jasper, A. Peedicayil, A. Regi, R. Sharma, A. Chauhan, V. Raut, R. Udani, S. Batra, A. Muthal-Rathore, S. Ramji, V. Zutshi, S. Balakrishnan, E. Eapen, G. Koshy, N. Ambardar, P. Vadakkepat, D. Vaidya, V. Lema, Y. Rijken, E. Tadesse, O. Dada, A. Sofekun, C. Ohiaeri, T. Runsewe-Abiodun, I. Adewole, A. Adeyemo, B. Brown, R. Oladokun, O. Adewale, N. Inimgba, C. John, R. Ogu, B. Ekele, A. Isah, B. Onankpa, R. Jamelle, D. Junejo, N. Ruby Faiz, F. Gul, A. Sherin, K. Bangash, G. Mahmud, K. Masud, N. Tasneem, S. Gassama, A. Soyei, P. Agarwal, V. Rajadurai, N. Pirani, S. Delport, P. Macdonald, R. Mokhondo, R. Pattinson, M. Zondo, M. Adhikari, N. Mnguni, J. Moodley, M. Carstens, G. Kirsten, W. Steyn, J. Van Zyl, A. Helwig, S. L. Jacobson, R. Panosche, E. Hammond, L. Masanganise

Research output: Contribution to journal › Article › peer-review

Abstract

Objective: The aim of this study was to assess long-term effects for women following the use of magnesium sulphate for pre-eclampsia. Design: Assessment at 2-3 years after delivery for women recruited to the Magpie Trial (recruitment in 1998-2001, ISRCTN 86938761), which compared magnesium sulphate with placebo for pre-eclampsia. Setting: Follow up after discharge from hospital at 125 centres in 19 countries across five continents. Population: A total of 7927 women were randomised at the follow-up centres. Of these women, 2544 were not included for logistic reasons and 601 excluded (109 at a centre where

Original language	English
Pages (from-to)	300-309
Number of pages	9
Journal	BJOG: An International Journal of Obstetrics and Gynaecology
Volume	114
Issue number	3
DOIs	https://doi.org/10.1111/j.1471-0528.2006.01166.x
Publication status	Published - Mar 2007

Keywords

Longterm follow-up
Magnesium sulphate
Pre-eclampsia
Randomised trial

Access to Document

10.1111/j.1471-0528.2006.01166.x

Cite this

Duley, L., Farrell, B., Armstrong, N., Spark, P., Roberts, B., Smyth, R., Tivnan, M., Laws, A., Corfield, N., Salter, A., Thorn, L., Altman, D., Yu, L. M., Abalos, E., Carroli, B., Dellepiane, L., Duarte, M., Fernandez, H., Giordano, D., ... Masanganise, L. (2007). The Magpie Trial: A randomised trial comparing magnesium sulphate with placebo for pre-eclampsia. Outcome for women at 2 years. BJOG: An International Journal of Obstetrics and Gynaecology, 114(3), 300-309. https://doi.org/10.1111/j.1471-0528.2006.01166.x

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title = "The Magpie Trial: A randomised trial comparing magnesium sulphate with placebo for pre-eclampsia. Outcome for women at 2 years",

abstract = "Objective: The aim of this study was to assess long-term effects for women following the use of magnesium sulphate for pre-eclampsia. Design: Assessment at 2-3 years after delivery for women recruited to the Magpie Trial (recruitment in 1998-2001, ISRCTN 86938761), which compared magnesium sulphate with placebo for pre-eclampsia. Setting: Follow up after discharge from hospital at 125 centres in 19 countries across five continents. Population: A total of 7927 women were randomised at the follow-up centres. Of these women, 2544 were not included for logistic reasons and 601 excluded (109 at a centre where",

keywords = "Longterm follow-up, Magnesium sulphate, Pre-eclampsia, Randomised trial",

author = "L. Duley and Barbara Farrell and Nina Armstrong and Patsy Spark and Barbara Roberts and Rebecca Smyth and Mary Tivnan and Anna Laws and Noelene Corfield and Annette Salter and Lisa Thorn and Douglas Altman and Yu, {Ly Mee} and Edgardo Abalos and Berenise Carroli and Lucrecia Dellepiane and Marina Duarte and Hebe Fernandez and Daniel Giordano and Mike Clarke and Alastair Gray and Edmund Hey and James Neilson and Judit Simon and Rory Collins and Anna Karaoglou and Richard Lilford and Stephen Robson and Ian Roberts and Peter Rubin and James Thornton and Sara Twaddle and Jos{\'e} Villar and Isabel Walker and Christopher Watkins and Lex Doyle and A. Bimbashi and E. Demalia and O. Gliozheni and A. Shpata and A. Karolinski and M. Lamas and M. Pesaresi and V. Wainer and W. Barbato and M. Paciocco and M. Bertin and E. Boiza and J. Castaldi and Y. Partida and C. Arias and M. Farri and G. Kerz and J. Aguirre and {De Sagastiz{\'a}bal}, M. and R. Falcone and E. Morales and G. Carroli and S. Krupitzky and S. L{\'o}pez and M. Palermo and {Montes Varela}, D. and H. Delprato and H. Camusso and M. Curioni and E. Ludmer and R. Brandi and R. Martin and W. Mesas and R. Taralli and M. Lezaola and M. Morosini and E. Andina and L. Bernal and M. Esti{\'u} and E. Ulens and {Ortiz De Speranza}, B. and A. Peyrano and M. Damiano and C. Saumench and J. Horn and M. Pritchard and V. Smith-Orr and M. Wilson and A. Lawrence and D. Watson and C. Crowther and J. Paynter and [Unknown] Ashrafunnessa and M. Mannan and M. Shahidullah and L. Shamsuddin and {Barros Santos}, C. and S. Freire and E. Melo and E. Cobo and E. Jaramillo and C. Cardozo and N. Fandi{\~n}o and H. Gait{\'a}n and L. Monta{\~n}o and J. Lozano and M. Rojas and {Breto Garc{\'i}{\'a}}, A. and {Fuentes Ramirez}, A. and {Garc{\'i}{\'a} M{\'i}r{\'a}s}, R. and S. Sampera and U. Farnot and E. G{\'o}mez and G. Rojas and R. Vald{\'e}s and {Abd El-Kreem}, H. and T. Al-Hussaini and E. Hammad and K. Danso and E. Kwapong and E. Ofosu-Barko and {Padmini Jasper}, M. and A. Peedicayil and A. Regi and R. Sharma and A. Chauhan and V. Raut and R. Udani and S. Batra and A. Muthal-Rathore and S. Ramji and V. Zutshi and S. Balakrishnan and E. Eapen and G. Koshy and N. Ambardar and P. Vadakkepat and D. Vaidya and V. Lema and Y. Rijken and E. Tadesse and O. Dada and A. Sofekun and C. Ohiaeri and T. Runsewe-Abiodun and I. Adewole and A. Adeyemo and B. Brown and R. Oladokun and O. Adewale and N. Inimgba and C. John and R. Ogu and B. Ekele and A. Isah and B. Onankpa and R. Jamelle and D. Junejo and {Ruby Faiz}, N. and F. Gul and A. Sherin and K. Bangash and G. Mahmud and K. Masud and N. Tasneem and S. Gassama and A. Soyei and P. Agarwal and V. Rajadurai and N. Pirani and S. Delport and P. Macdonald and R. Mokhondo and R. Pattinson and M. Zondo and M. Adhikari and N. Mnguni and J. Moodley and M. Carstens and G. Kirsten and W. Steyn and {Van Zyl}, J. and A. Helwig and Jacobson, {S. L.} and R. Panosche and E. Hammond and L. Masanganise",

year = "2007",

month = mar,

doi = "10.1111/j.1471-0528.2006.01166.x",

language = "English",

volume = "114",

pages = "300--309",

journal = "BJOG: An International Journal of Obstetrics and Gynaecology",

issn = "1471-0528",

publisher = "John Wiley & Sons Ltd",

number = "3",

}

Duley, L, Farrell, B, Armstrong, N, Spark, P, Roberts, B, Smyth, R, Tivnan, M, Laws, A, Corfield, N, Salter, A, Thorn, L, Altman, D, Yu, LM, Abalos, E, Carroli, B, Dellepiane, L, Duarte, M, Fernandez, H, Giordano, D, Clarke, M, Gray, A, Hey, E, Neilson, J, Simon, J, Collins, R, Karaoglou, A, Lilford, R, Robson, S, Roberts, I, Rubin, P, Thornton, J, Twaddle, S, Villar, J, Walker, I, Watkins, C, Doyle, L, Bimbashi, A, Demalia, E, Gliozheni, O, Shpata, A, Karolinski, A, Lamas, M, Pesaresi, M, Wainer, V, Barbato, W, Paciocco, M, Bertin, M, Boiza, E, Castaldi, J, Partida, Y, Arias, C, Farri, M, Kerz, G, Aguirre, J, De Sagastizábal, M, Falcone, R, Morales, E, Carroli, G, Krupitzky, S, López, S, Palermo, M, Montes Varela, D, Delprato, H, Camusso, H, Curioni, M, Ludmer, E, Brandi, R, Martin, R, Mesas, W, Taralli, R, Lezaola, M, Morosini, M, Andina, E, Bernal, L, Estiú, M, Ulens, E, Ortiz De Speranza, B, Peyrano, A, Damiano, M, Saumench, C, Horn, J, Pritchard, M, Smith-Orr, V, Wilson, M, Lawrence, A, Watson, D, Crowther, C, Paynter, J, Ashrafunnessa, U, Mannan, M, Shahidullah, M, Shamsuddin, L, Barros Santos, C, Freire, S, Melo, E, Cobo, E, Jaramillo, E, Cardozo, C, Fandiño, N, Gaitán, H, Montaño, L, Lozano, J, Rojas, M, Breto Garcíá, A, Fuentes Ramirez, A, Garcíá Mírás, R, Sampera, S, Farnot, U, Gómez, E, Rojas, G, Valdés, R, Abd El-Kreem, H, Al-Hussaini, T, Hammad, E, Danso, K, Kwapong, E, Ofosu-Barko, E, Padmini Jasper, M, Peedicayil, A, Regi, A, Sharma, R, Chauhan, A, Raut, V, Udani, R, Batra, S, Muthal-Rathore, A, Ramji, S, Zutshi, V, Balakrishnan, S, Eapen, E, Koshy, G, Ambardar, N, Vadakkepat, P, Vaidya, D, Lema, V, Rijken, Y, Tadesse, E, Dada, O, Sofekun, A, Ohiaeri, C, Runsewe-Abiodun, T, Adewole, I, Adeyemo, A, Brown, B, Oladokun, R, Adewale, O, Inimgba, N, John, C, Ogu, R, Ekele, B, Isah, A, Onankpa, B, Jamelle, R, Junejo, D, Ruby Faiz, N, Gul, F, Sherin, A, Bangash, K, Mahmud, G, Masud, K, Tasneem, N, Gassama, S, Soyei, A, Agarwal, P, Rajadurai, V, Pirani, N, Delport, S, Macdonald, P, Mokhondo, R, Pattinson, R, Zondo, M, Adhikari, M, Mnguni, N, Moodley, J, Carstens, M, Kirsten, G, Steyn, W, Van Zyl, J, Helwig, A, Jacobson, SL, Panosche, R, Hammond, E & Masanganise, L 2007, 'The Magpie Trial: A randomised trial comparing magnesium sulphate with placebo for pre-eclampsia. Outcome for women at 2 years', BJOG: An International Journal of Obstetrics and Gynaecology, vol. 114, no. 3, pp. 300-309. https://doi.org/10.1111/j.1471-0528.2006.01166.x

TY - JOUR

T1 - The Magpie Trial: A randomised trial comparing magnesium sulphate with placebo for pre-eclampsia. Outcome for women at 2 years

AU - Duley, L.

AU - Farrell, Barbara

AU - Armstrong, Nina

AU - Spark, Patsy

AU - Roberts, Barbara

AU - Smyth, Rebecca

AU - Tivnan, Mary

AU - Laws, Anna

AU - Corfield, Noelene

AU - Salter, Annette

AU - Thorn, Lisa

AU - Altman, Douglas

AU - Yu, Ly Mee

AU - Abalos, Edgardo

AU - Carroli, Berenise

AU - Dellepiane, Lucrecia

AU - Duarte, Marina

AU - Fernandez, Hebe

AU - Giordano, Daniel

AU - Clarke, Mike

AU - Gray, Alastair

AU - Hey, Edmund

AU - Neilson, James

AU - Simon, Judit

AU - Collins, Rory

AU - Karaoglou, Anna

AU - Lilford, Richard

AU - Robson, Stephen

AU - Roberts, Ian

AU - Rubin, Peter

AU - Thornton, James

AU - Twaddle, Sara

AU - Villar, José

AU - Walker, Isabel

AU - Watkins, Christopher

AU - Doyle, Lex

AU - Bimbashi, A.

AU - Demalia, E.

AU - Gliozheni, O.

AU - Shpata, A.

AU - Karolinski, A.

AU - Lamas, M.

AU - Pesaresi, M.

AU - Wainer, V.

AU - Barbato, W.

AU - Paciocco, M.

AU - Bertin, M.

AU - Boiza, E.

AU - Castaldi, J.

AU - Partida, Y.

AU - Arias, C.

AU - Farri, M.

AU - Kerz, G.

AU - Aguirre, J.

AU - De Sagastizábal, M.

AU - Falcone, R.

AU - Morales, E.

AU - Carroli, G.

AU - Krupitzky, S.

AU - López, S.

AU - Palermo, M.

AU - Montes Varela, D.

AU - Delprato, H.

AU - Camusso, H.

AU - Curioni, M.

AU - Ludmer, E.

AU - Brandi, R.

AU - Martin, R.

AU - Mesas, W.

AU - Taralli, R.

AU - Lezaola, M.

AU - Morosini, M.

AU - Andina, E.

AU - Bernal, L.

AU - Estiú, M.

AU - Ulens, E.

AU - Ortiz De Speranza, B.

AU - Peyrano, A.

AU - Damiano, M.

AU - Saumench, C.

AU - Horn, J.

AU - Pritchard, M.

AU - Smith-Orr, V.

AU - Wilson, M.

AU - Lawrence, A.

AU - Watson, D.

AU - Crowther, C.

AU - Paynter, J.

AU - Ashrafunnessa, [Unknown]

AU - Mannan, M.

AU - Shahidullah, M.

AU - Shamsuddin, L.

AU - Barros Santos, C.

AU - Freire, S.

AU - Melo, E.

AU - Cobo, E.

AU - Jaramillo, E.

AU - Cardozo, C.

AU - Fandiño, N.

AU - Gaitán, H.

AU - Montaño, L.

AU - Lozano, J.

AU - Rojas, M.

AU - Breto Garcíá, A.

AU - Fuentes Ramirez, A.

AU - Garcíá Mírás, R.

AU - Sampera, S.

AU - Farnot, U.

AU - Gómez, E.

AU - Rojas, G.

AU - Valdés, R.

AU - Abd El-Kreem, H.

AU - Al-Hussaini, T.

AU - Hammad, E.

AU - Danso, K.

AU - Kwapong, E.

AU - Ofosu-Barko, E.

AU - Padmini Jasper, M.

AU - Peedicayil, A.

AU - Regi, A.

AU - Sharma, R.

AU - Chauhan, A.

AU - Raut, V.

AU - Udani, R.

AU - Batra, S.

AU - Muthal-Rathore, A.

AU - Ramji, S.

AU - Zutshi, V.

AU - Balakrishnan, S.

AU - Eapen, E.

AU - Koshy, G.

AU - Ambardar, N.

AU - Vadakkepat, P.

AU - Vaidya, D.

AU - Lema, V.

AU - Rijken, Y.

AU - Tadesse, E.

AU - Dada, O.

AU - Sofekun, A.

AU - Ohiaeri, C.

AU - Runsewe-Abiodun, T.

AU - Adewole, I.

AU - Adeyemo, A.

AU - Brown, B.

AU - Oladokun, R.

AU - Adewale, O.

AU - Inimgba, N.

AU - John, C.

AU - Ogu, R.

AU - Ekele, B.

AU - Isah, A.

AU - Onankpa, B.

AU - Jamelle, R.

AU - Junejo, D.

AU - Ruby Faiz, N.

AU - Gul, F.

AU - Sherin, A.

AU - Bangash, K.

AU - Mahmud, G.

AU - Masud, K.

AU - Tasneem, N.

AU - Gassama, S.

AU - Soyei, A.

AU - Agarwal, P.

AU - Rajadurai, V.

AU - Pirani, N.

AU - Delport, S.

AU - Macdonald, P.

AU - Mokhondo, R.

AU - Pattinson, R.

AU - Zondo, M.

AU - Adhikari, M.

AU - Mnguni, N.

AU - Moodley, J.

AU - Carstens, M.

AU - Kirsten, G.

AU - Steyn, W.

AU - Van Zyl, J.

AU - Helwig, A.

AU - Jacobson, S. L.

AU - Panosche, R.

AU - Hammond, E.

AU - Masanganise, L.

PY - 2007/3

Y1 - 2007/3

N2 - Objective: The aim of this study was to assess long-term effects for women following the use of magnesium sulphate for pre-eclampsia. Design: Assessment at 2-3 years after delivery for women recruited to the Magpie Trial (recruitment in 1998-2001, ISRCTN 86938761), which compared magnesium sulphate with placebo for pre-eclampsia. Setting: Follow up after discharge from hospital at 125 centres in 19 countries across five continents. Population: A total of 7927 women were randomised at the follow-up centres. Of these women, 2544 were not included for logistic reasons and 601 excluded (109 at a centre where

AB - Objective: The aim of this study was to assess long-term effects for women following the use of magnesium sulphate for pre-eclampsia. Design: Assessment at 2-3 years after delivery for women recruited to the Magpie Trial (recruitment in 1998-2001, ISRCTN 86938761), which compared magnesium sulphate with placebo for pre-eclampsia. Setting: Follow up after discharge from hospital at 125 centres in 19 countries across five continents. Population: A total of 7927 women were randomised at the follow-up centres. Of these women, 2544 were not included for logistic reasons and 601 excluded (109 at a centre where

KW - Longterm follow-up

KW - Magnesium sulphate

KW - Pre-eclampsia

KW - Randomised trial

U2 - 10.1111/j.1471-0528.2006.01166.x

DO - 10.1111/j.1471-0528.2006.01166.x

M3 - Article

SN - 1471-0528

VL - 114

SP - 300

EP - 309

JO - BJOG: An International Journal of Obstetrics and Gynaecology

JF - BJOG: An International Journal of Obstetrics and Gynaecology

IS - 3

ER -

The Magpie Trial: A randomised trial comparing magnesium sulphate with placebo for pre-eclampsia. Outcome for women at 2 years

Abstract

Keywords

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