Abstract
Aims/hypothesis: The commercially available Neuropad test was developed as a simple visual indicator test to evaluate diabetic neuropathy. It uses a colour change to define the integrity of skin sympathetic cholinergic innervation. We compared the results of Neuropad assessment in the foot with established measures of somatic and autonomic neuropathy. Methods: Fifty-seven diabetic patients underwent Neuropad assessment, quantitative sensory and autonomic function testing, and evaluation of intra-epidermal nerve fibre density in foot skin biopsies. Results: Neuropad responses correlated with the neuropathy disability score (rs=0.450, p
Original language | English |
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Pages (from-to) | 1046-1050 |
Number of pages | 4 |
Journal | Diabetologia |
Volume | 51 |
Issue number | 6 |
DOIs | |
Publication status | Published - Jun 2008 |
Keywords
- Autonomic neuropathy
- Diabetic neuropathy
- Skin innervation
- Sudomotor dysfunction