The Neuropad test: A visual indicator test for human diabetic neuropathy

C. Quattrini, M. Jeziorska, M. Tavakoli, P. Begum, A. J M Boulton, R. A. Malik

    Research output: Contribution to journalArticlepeer-review


    Aims/hypothesis: The commercially available Neuropad test was developed as a simple visual indicator test to evaluate diabetic neuropathy. It uses a colour change to define the integrity of skin sympathetic cholinergic innervation. We compared the results of Neuropad assessment in the foot with established measures of somatic and autonomic neuropathy. Methods: Fifty-seven diabetic patients underwent Neuropad assessment, quantitative sensory and autonomic function testing, and evaluation of intra-epidermal nerve fibre density in foot skin biopsies. Results: Neuropad responses correlated with the neuropathy disability score (rs=0.450, p
    Original languageEnglish
    Pages (from-to)1046-1050
    Number of pages4
    Issue number6
    Publication statusPublished - Jun 2008


    • Autonomic neuropathy
    • Diabetic neuropathy
    • Skin innervation
    • Sudomotor dysfunction


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