The ONCO-I2b2 project: Integrating biobank information and clinical data to support translational research in oncology

Daniele Segagni*, Valentina Tibollo, Arianna Dagliati, Leonardo Perinati, Alberto Zambelli, Silvia Priori, Riccardo Bellazzi

*Corresponding author for this work

Research output: Chapter in Book/Conference proceedingConference contributionpeer-review

Abstract

The University of Pavia and the IRCCS Fondazione Salvatore Maugeri of Pavia (FSM), has recently started an IT initiative to support clinical research in oncology, called ONCO-i2b2. ONCO-i2b2, funded by the Lombardia region, grounds on the software developed by the Informatics for Integrating Biology and the Bedside (i2b2) NIH project. Using i2b2 and new software modules purposely designed, data coming from multiple sources are integrated and jointly queried. The core of the integration process stands in retrieving and merging data from the biobank management software and from the FSM hospital information system. The integration process is based on a ontology of the problem domain and on open-source software integration modules. A Natural Language Processing module has been implemented, too. This module automatically extracts clinical information of oncology patients from unstructured medical records. The system currently manages more than two thousands patients and will be further implemented and improved in the next two years.

Original languageEnglish
Title of host publicationUser Centred Networked Health Care - Proceedings of MIE 2011
PublisherIOS Press
Pages887-891
Number of pages5
ISBN (Print)9781607508052
DOIs
Publication statusPublished - 1 Jan 2011
Event23rd International Conference of the European Federation for Medical Informatics, MIE 2011 - Oslo, Norway
Duration: 28 Aug 201131 Aug 2011

Publication series

NameStudies in Health Technology and Informatics
Volume169
ISSN (Print)0926-9630
ISSN (Electronic)1879-8365

Conference

Conference23rd International Conference of the European Federation for Medical Informatics, MIE 2011
Country/TerritoryNorway
CityOslo
Period28/08/1131/08/11

Keywords

  • Biobanks
  • Hospital information system integration
  • I2B2
  • Natural language processing
  • Oncology research
  • Translational research

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