The pathophysiology of the chronic cardiorenal syndrome: a magnetic resonance imaging study.

Tobias Breidthardt, Eleanor F Cox, Iain Squire, Aghogho Odudu, Nur Farhayu Omar, Mohamed Tarek Eldehni, Susan T Francis, Christopher W McIntyre

    Research output: Contribution to journalArticlepeer-review

    Abstract

    OBJECTIVE: To study the association of renal function with renal perfusion and renal parenchymal structure (T1 relaxation) in patients with chronic heart failure (HF). METHODS: After IRB approval, 40 participants were enrolled according to HF and renal function status [10 healthy volunteers  60 ml/min/1.73 m(2); 10 HF patients eGFR  0.01) and was higher in HF patients compared to volunteers (1121 ± 102 ms vs. 1054 ± 65 ms;p = 0.03). T1 relaxation was selectively prolonged in HF patients with RD (1169 ms ± 100 vs. HF without RD 1067 ms ± 79;p = 0.047). In linear regression analyses coronary artery disease (p = 0.01), hypertension (p = 0.04), and diabetes mellitus (p 
    Original languageEnglish
    JournalEuropean Radiology
    DOIs
    Publication statusPublished - 11 Jan 2015

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