The Pfam protein families database

Alex Bateman, Lachlan Coin, Richard Durbin, Robert D. Finn, Volker Hollich, Sam Griffiths-Jones, Ajay Khanna, Mhairi Marshall, Simon Moxon, Erik L L Sonnhammer, David J. Studholme, Corin Yeats, Sean R. Eddy

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Pfam is a large collection of protein families and domains. Over the past 2 years the number of families in Pfam has doubled and now stands at 6190 (version 10.0). Methodology improvements for searching the Pfam collection locally as well as via the web are described. Other recent innovations include modelling of discontinuous domains allowing Pfam domain definitions to be closer to those found in structure databases. Pfam is available on the web in the UK (http:/www.sanger.ac.uk/Software/Pfam/), the USA (http://pfam.wustl.edu/), France (http://pfam.jouy.inra.fr/) and Sweden (http://Pfam.cgb.ki.se/).
    Original languageEnglish
    Pages (from-to)D138-D141
    JournalNucleic acids research.
    Volume32
    DOIs
    Publication statusPublished - 1 Jan 2004

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