The potential of pharmacogenetics in optimizing the use of methotrexate for psoriasis

R. B. Warren; C. E M Griffiths

doi:10.1111/j.1365-2133.2005.06880.x

The potential of pharmacogenetics in optimizing the use of methotrexate for psoriasis

Research output: Contribution to journal › Article › peer-review

Abstract

The study of pharmacogenetics will optimize the use of systemic therapies in dermatology. Directed prescription of azathioprine dependent on phenotypic expression of the thiopurine methyltransferase gene is now accepted practice. To some extent other, older drugs have been neglected. We look at the role that pharmacogenetics could play in the use of methotrexate for psoriasis, focusing on known polymorphisms in the folate metabolic pathway. © 2005 British Association of Dermatologists.

Original language	English
Pages (from-to)	869-873
Number of pages	4
Journal	British Journal of Dermatology
Volume	153
Issue number	5
DOIs	https://doi.org/10.1111/j.1365-2133.2005.06880.x
Publication status	Published - Nov 2005

Keywords

Folate
Genetics
Methotrexate
Pharmacogenetics
Psoriasis

Access to Document

10.1111/j.1365-2133.2005.06880.x

Cite this

@article{38b1a4cb96b84b04922f643fcc01362b,

title = "The potential of pharmacogenetics in optimizing the use of methotrexate for psoriasis",

abstract = "The study of pharmacogenetics will optimize the use of systemic therapies in dermatology. Directed prescription of azathioprine dependent on phenotypic expression of the thiopurine methyltransferase gene is now accepted practice. To some extent other, older drugs have been neglected. We look at the role that pharmacogenetics could play in the use of methotrexate for psoriasis, focusing on known polymorphisms in the folate metabolic pathway. {\textcopyright} 2005 British Association of Dermatologists.",

keywords = "Folate, Genetics, Methotrexate, Pharmacogenetics, Psoriasis",

author = "Warren, {R. B.} and Griffiths, {C. E M}",

year = "2005",

month = nov,

doi = "10.1111/j.1365-2133.2005.06880.x",

language = "English",

volume = "153",

pages = "869--873",

journal = "British Journal of Dermatology",

issn = "0007-0963",

publisher = "Oxford University Press",

number = "5",

}

TY - JOUR

T1 - The potential of pharmacogenetics in optimizing the use of methotrexate for psoriasis

AU - Warren, R. B.

AU - Griffiths, C. E M

PY - 2005/11

Y1 - 2005/11

N2 - The study of pharmacogenetics will optimize the use of systemic therapies in dermatology. Directed prescription of azathioprine dependent on phenotypic expression of the thiopurine methyltransferase gene is now accepted practice. To some extent other, older drugs have been neglected. We look at the role that pharmacogenetics could play in the use of methotrexate for psoriasis, focusing on known polymorphisms in the folate metabolic pathway. © 2005 British Association of Dermatologists.

AB - The study of pharmacogenetics will optimize the use of systemic therapies in dermatology. Directed prescription of azathioprine dependent on phenotypic expression of the thiopurine methyltransferase gene is now accepted practice. To some extent other, older drugs have been neglected. We look at the role that pharmacogenetics could play in the use of methotrexate for psoriasis, focusing on known polymorphisms in the folate metabolic pathway. © 2005 British Association of Dermatologists.

KW - Folate

KW - Genetics

KW - Methotrexate

KW - Pharmacogenetics

KW - Psoriasis

U2 - 10.1111/j.1365-2133.2005.06880.x

DO - 10.1111/j.1365-2133.2005.06880.x

M3 - Article

C2 - 16225593

SN - 0007-0963

VL - 153

SP - 869

EP - 873

JO - British Journal of Dermatology

JF - British Journal of Dermatology

IS - 5

ER -

The potential of pharmacogenetics in optimizing the use of methotrexate for psoriasis

Abstract

Keywords

Access to Document

Fingerprint

Cite this