The pro-apoptotic JNK scaffold POSH/SH3RF1 mediates CHMP2BIntron5-associated toxicity in animal models of frontotemporal dementia

Biochemistry, Genetics and Molecular Biology

• Mammalian Model 100%
• N-Terminus 50%
• Mouse 50%
• Phosphotransferase 50%
• Kinase 50%
• Cell Death 50%
• SH3 Domain 50%
• Fruit Fly Model 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Frontotemporal Dementia 100%
• Mouse 16%
• Fruit Fly Model 16%
• Phosphotransferase 16%
• Prematurity 16%
• Neuroprotective Agent 16%
• Lethality 16%

Neuroscience

• Frontotemporal Dementia 100%
• Kinase 16%
• Neuroprotective Agent 16%
• SH3 Domain 16%
• Cell Death 16%
• Amino Terminal Sequence 16%