The psychosocial outcome of pregnancy in women with psychotic disorders

Louise Michele Howard, Claudia Goss, Morven Leese, Louis Appleby, Graham Thornicroft

    Research output: Contribution to journalArticlepeer-review


    Objective: To investigate the psychosocial outcome of pregnancies in women with a history of psychotic disorder in an epidemiologically representative sample and to determine the predictors of having a baby looked after by social services in the first year of life. Method: Historical matched controlled cohort study and nested case control study using the General Practice Research Database (GPRD), an anonymised primary care database, in women with a history of psychotic disorders who gave birth in 1996-1998 (199 cases and 787 controls). Results: Twenty-seven percent of cases had a psychotic episode and a further 38% had nonpsychotic depression in the first year after birth. Women with nonaffective psychoses were at a significantly higher risk of postnatal depression compared with controls (adjusted rate ratio 2.07, 95% CI 1.45-2.96, p
    Original languageEnglish
    Pages (from-to)49-60
    Number of pages11
    JournalSchizophrenia Research
    Issue number1
    Publication statusPublished - 1 Nov 2004


    • Parenting
    • Postnatal depression
    • Primary health care
    • Schizophrenia


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