The second generation HRRT - A multi-centre scanner performance investigation

Vesna Sossi; Hugo W A M De Jong; W. Craig Barker; Peter Bloomfield; Ziad Burbar; Marie Laure Camborde; Claude Comtat; Lars A. Eriksson; Sylvain Houle; David Keator; Christof Knöß; Roman Krais; Adriaan A. Lammertsma; Arman Rahmim; Mérence Sibomana; Mika Teräs; Christopher J. Thompson; Régine Trébossen; John Votaw; Matthew Walker; Klaus Wienhard; Dean F. Wong

doi:10.1109/NSSMIC.2005.1596770

The second generation HRRT - A multi-centre scanner performance investigation

Vesna Sossi, Hugo W A M De Jong, W. Craig Barker, Peter Bloomfield, Ziad Burbar, Marie Laure Camborde, Claude Comtat, Lars A. Eriksson, Sylvain Houle, David Keator, Christof Knöß, Roman Krais, Adriaan A. Lammertsma, Arman Rahmim, Mérence Sibomana, Mika Teräs, Christopher J. Thompson, Régine Trébossen, John Votaw, Matthew WalkerKlaus Wienhard, Dean F. Wong

Research output: Chapter in Book/Conference proceeding › Conference contribution

Abstract

The high resolution research tomograph (HRRT) is one of the most complex existing Positron Emission Tomographs: it is the only human size scanner capable of decoding the depth of the γ-ray interaction in the crystal, using a lutetium LSO/LYSO phoswitch detector arrangement. In this study we determined basic scanner hardware characteristics, such as scanner data acquisition stability, and their variability across eleven centres. In addition a subset of the NEMA NU-2001 standards measurements was performed. We found (i) significant variability in the DOI decoding results between centres, (ii) a trend toward an increasing number of detected true coincident events as a function of elapsed time from scanner calibration likely due to a shifting energy spectrum, (iii) a count-rate dependent layer identification, (iv) scatter fraction ranging from ∼ 42% to 54% where the variability was partly related to the shifting of the energy spectrum, (v) sensitivity ranging from ∼ 5.5% to 6.5% across centres, (vi) resolution of ∼ (2.5mm)3, fairly consistent across centres, (vii) image quality which is very comparable to other scanners. ©2005 IEEE.

Original language	English
Title of host publication	IEEE Nuclear Science Symposium Conference Record\|IEEE Nucl. Sci. Symp. Conf. Rec.
Publisher	IEEE
Pages	2195-2199
Number of pages	4
Volume	4
ISBN (Print)	0780392213, 9780780392212
DOIs	https://doi.org/10.1109/NSSMIC.2005.1596770
Publication status	Published - 2005
Event	Nuclear Science Symposium Conference Record, 2005 IEEE - Duration: 1 Jul 2005 → …

Conference

Conference	Nuclear Science Symposium Conference Record, 2005 IEEE
Period	1/07/05 → …

Keywords

Depth of interaction
ECAT HRRT
High resolution research tomograph
Performance study
PET
Positron emission tomography
Resolution
Scatter fraction
Sensitivity
Stability

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10.1109/NSSMIC.2005.1596770

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Sossi, V., De Jong, H. W. A. M., Barker, W. C., Bloomfield, P., Burbar, Z., Camborde, M. L., Comtat, C., Eriksson, L. A., Houle, S., Keator, D., Knöß, C., Krais, R., Lammertsma, A. A., Rahmim, A., Sibomana, M., Teräs, M., Thompson, C. J., Trébossen, R., Votaw, J., ... Wong, D. F. (2005). The second generation HRRT - A multi-centre scanner performance investigation. In IEEE Nuclear Science Symposium Conference Record|IEEE Nucl. Sci. Symp. Conf. Rec. (Vol. 4, pp. 2195-2199). IEEE. https://doi.org/10.1109/NSSMIC.2005.1596770

@inproceedings{7ffbe23e444840f481e45abddd53a930,

title = "The second generation HRRT - A multi-centre scanner performance investigation",

abstract = "The high resolution research tomograph (HRRT) is one of the most complex existing Positron Emission Tomographs: it is the only human size scanner capable of decoding the depth of the γ-ray interaction in the crystal, using a lutetium LSO/LYSO phoswitch detector arrangement. In this study we determined basic scanner hardware characteristics, such as scanner data acquisition stability, and their variability across eleven centres. In addition a subset of the NEMA NU-2001 standards measurements was performed. We found (i) significant variability in the DOI decoding results between centres, (ii) a trend toward an increasing number of detected true coincident events as a function of elapsed time from scanner calibration likely due to a shifting energy spectrum, (iii) a count-rate dependent layer identification, (iv) scatter fraction ranging from ∼ 42% to 54% where the variability was partly related to the shifting of the energy spectrum, (v) sensitivity ranging from ∼ 5.5% to 6.5% across centres, (vi) resolution of ∼ (2.5mm)3, fairly consistent across centres, (vii) image quality which is very comparable to other scanners. {\textcopyright}2005 IEEE.",

keywords = "Depth of interaction, ECAT HRRT, High resolution research tomograph, Performance study, PET, Positron emission tomography, Resolution, Scatter fraction, Sensitivity, Stability",

author = "Vesna Sossi and {De Jong}, {Hugo W A M} and Barker, {W. Craig} and Peter Bloomfield and Ziad Burbar and Camborde, {Marie Laure} and Claude Comtat and Eriksson, {Lars A.} and Sylvain Houle and David Keator and Christof Kn{\"o}{\ss} and Roman Krais and Lammertsma, {Adriaan A.} and Arman Rahmim and M{\'e}rence Sibomana and Mika Ter{\"a}s and Thompson, {Christopher J.} and R{\'e}gine Tr{\'e}bossen and John Votaw and Matthew Walker and Klaus Wienhard and Wong, {Dean F.}",

year = "2005",

doi = "10.1109/NSSMIC.2005.1596770",

language = "English",

isbn = "0780392213",

volume = "4",

pages = "2195--2199",

booktitle = "IEEE Nuclear Science Symposium Conference Record|IEEE Nucl. Sci. Symp. Conf. Rec.",

publisher = "IEEE",

address = "United States",

note = "Nuclear Science Symposium Conference Record, 2005 IEEE ; Conference date: 01-07-2005",

}

Sossi, V, De Jong, HWAM, Barker, WC, Bloomfield, P, Burbar, Z, Camborde, ML, Comtat, C, Eriksson, LA, Houle, S, Keator, D, Knöß, C, Krais, R, Lammertsma, AA, Rahmim, A, Sibomana, M, Teräs, M, Thompson, CJ, Trébossen, R, Votaw, J, Walker, M, Wienhard, K & Wong, DF 2005, The second generation HRRT - A multi-centre scanner performance investigation. in IEEE Nuclear Science Symposium Conference Record|IEEE Nucl. Sci. Symp. Conf. Rec.. vol. 4, IEEE, pp. 2195-2199, Nuclear Science Symposium Conference Record, 2005 IEEE, 1/07/05. https://doi.org/10.1109/NSSMIC.2005.1596770

TY - GEN

T1 - The second generation HRRT - A multi-centre scanner performance investigation

AU - Sossi, Vesna

AU - De Jong, Hugo W A M

AU - Barker, W. Craig

AU - Bloomfield, Peter

AU - Burbar, Ziad

AU - Camborde, Marie Laure

AU - Comtat, Claude

AU - Eriksson, Lars A.

AU - Houle, Sylvain

AU - Keator, David

AU - Knöß, Christof

AU - Krais, Roman

AU - Lammertsma, Adriaan A.

AU - Rahmim, Arman

AU - Sibomana, Mérence

AU - Teräs, Mika

AU - Thompson, Christopher J.

AU - Trébossen, Régine

AU - Votaw, John

AU - Walker, Matthew

AU - Wienhard, Klaus

AU - Wong, Dean F.

PY - 2005

Y1 - 2005

N2 - The high resolution research tomograph (HRRT) is one of the most complex existing Positron Emission Tomographs: it is the only human size scanner capable of decoding the depth of the γ-ray interaction in the crystal, using a lutetium LSO/LYSO phoswitch detector arrangement. In this study we determined basic scanner hardware characteristics, such as scanner data acquisition stability, and their variability across eleven centres. In addition a subset of the NEMA NU-2001 standards measurements was performed. We found (i) significant variability in the DOI decoding results between centres, (ii) a trend toward an increasing number of detected true coincident events as a function of elapsed time from scanner calibration likely due to a shifting energy spectrum, (iii) a count-rate dependent layer identification, (iv) scatter fraction ranging from ∼ 42% to 54% where the variability was partly related to the shifting of the energy spectrum, (v) sensitivity ranging from ∼ 5.5% to 6.5% across centres, (vi) resolution of ∼ (2.5mm)3, fairly consistent across centres, (vii) image quality which is very comparable to other scanners. ©2005 IEEE.

AB - The high resolution research tomograph (HRRT) is one of the most complex existing Positron Emission Tomographs: it is the only human size scanner capable of decoding the depth of the γ-ray interaction in the crystal, using a lutetium LSO/LYSO phoswitch detector arrangement. In this study we determined basic scanner hardware characteristics, such as scanner data acquisition stability, and their variability across eleven centres. In addition a subset of the NEMA NU-2001 standards measurements was performed. We found (i) significant variability in the DOI decoding results between centres, (ii) a trend toward an increasing number of detected true coincident events as a function of elapsed time from scanner calibration likely due to a shifting energy spectrum, (iii) a count-rate dependent layer identification, (iv) scatter fraction ranging from ∼ 42% to 54% where the variability was partly related to the shifting of the energy spectrum, (v) sensitivity ranging from ∼ 5.5% to 6.5% across centres, (vi) resolution of ∼ (2.5mm)3, fairly consistent across centres, (vii) image quality which is very comparable to other scanners. ©2005 IEEE.

KW - Depth of interaction

KW - ECAT HRRT

KW - High resolution research tomograph

KW - Performance study

KW - PET

KW - Positron emission tomography

KW - Resolution

KW - Scatter fraction

KW - Sensitivity

KW - Stability

U2 - 10.1109/NSSMIC.2005.1596770

DO - 10.1109/NSSMIC.2005.1596770

M3 - Conference contribution

SN - 0780392213

SN - 9780780392212

VL - 4

SP - 2195

EP - 2199

BT - IEEE Nuclear Science Symposium Conference Record|IEEE Nucl. Sci. Symp. Conf. Rec.

PB - IEEE

T2 - Nuclear Science Symposium Conference Record, 2005 IEEE

Y2 - 1 July 2005

ER -

The second generation HRRT - A multi-centre scanner performance investigation

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Keywords

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