The Silent Undertakers: Macrophages Programmed for Efferocytosis

Judith E. Allen*, Dominik Rückerl

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review

Abstract

Two recent Immunity papers provide new insight into efferocytosis by tissue-resident macrophages. Baratin et al. (2017) identify a resident macrophage population in the T cell zone of lymph nodes responsible for the silent uptake of vast numbers of apoptotic cells. Roberts et al. (2017) find that resident macrophages can be programmed by local tissue signals not to respond to the nucleic acid of apoptotic cells. Two recent Immunity papers provide new insight into efferocytosis by tissue-resident macrophages. Baratin et al. (2017) identify a resident macrophage population in the T cell zone of lymph nodes responsible for the silent uptake of vast numbers of apoptotic cells. Roberts et al. (2017) find that resident macrophages can be programmed by local tissue signals not to respond to the nucleic acid of apoptotic cells.

Original languageEnglish
Pages (from-to)810-812
Number of pages3
JournalImmunity
Volume47
Issue number5
DOIs
Publication statusPublished - 21 Nov 2017

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