The UK DNA banking network: A "fair access'' biobank

Martin Yuille, Katherine Dixon, Andrew Platt, Simon Pullum, David Lewis, Alistair Hall, William Ollier

    Research output: Contribution to journalArticlepeer-review


    The UK DNA Banking Network (UDBN) is a secondary biobank: it aggregates and manages resources (samples and data) originated by others. The network comprises, on the one hand, investigator groups led by clinicians each with a distinct disease specialism and, on the other hand, a research infrastructure to manage samples and data. The infrastructure addresses the problem of providing secure quality-assured accrual, storage, replenishment and distribution capacities for samples and of facilitating access to DNA aliquots and data for new peerreviewed studies in genetic epidemiology. 'Fair access' principles and practices have been pragmatically developed that, unlike open access policies in this area, are not cumbersome but, rather, are fit for the purpose of expediting new study designs and their implementation. UDBN has so far distributed > 60,000 samples for major genotyping studies yielding >10 billion genotypes. It provides a working model that can inform progress in biobanking nationally, across Europe and internationally. © Springer Science+Business Media B.V. 2009.
    Original languageEnglish
    Pages (from-to)241-251
    Number of pages10
    JournalCell and Tissue Banking
    Issue number3
    Publication statusPublished - Aug 2010


    • Biobanking
    • Genetic epidemiology
    • Research infrastructure


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