The ultra high risk approach to define psychosis risk

Alison R. Yung, Paolo Fusar-Poli, Barnaby Nelson

    Research output: Contribution to journalArticlepeer-review


    Although prodromal symptoms of psychosis have long been recognized, the clinical management of psychotic disorders conventionally begins at the first episode of frank psychosis, and, until recently, the period immediately preceding the first episode received relatively little attention. Over the last fifteen years, there has been increasing academic and clinical interest in people presenting with potentially prodromal symptoms. This clinical syndrome has been termed an "At Risk Mental State", and operationalised criteria, the "Ultra High Risk (UHR)", or "Clinical High Risk" criteria, have been developed to identify the syndrome. We will review here the mainstreams of the UHR paradigms focusing on the conceptual basis, potentials and limtations in current psychiatric research. © 2012 Bentham Science Publishers.
    Original languageEnglish
    Pages (from-to)346-350
    Number of pages4
    JournalCurrent Pharmaceutical Design
    Issue number4
    Publication statusPublished - Jan 2012


    • Prodrome
    • Psychosis
    • Schizophrenia


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