The unrecognized prevalence of chronic kidney disease in diabetes

Rachel J. Middleton; Robert N. Foley; Janet Hegarty; Ching M. Cheung; Patrick McElduff; J. Martin Gibson; Philip A. Kalra; Donal J. O'Donoghue; John P. New

doi:10.1093/ndt/gfi163

The unrecognized prevalence of chronic kidney disease in diabetes

Rachel J. Middleton, Robert N. Foley, Janet Hegarty, Ching M. Cheung, Patrick McElduff, J. Martin Gibson, Philip A. Kalra, Donal J. O'Donoghue, John P. New

Research output: Contribution to journal › Article › peer-review

Abstract

Background: Diabetes mellitus and chronic kidney disease (CKD) are common and exhibit synergistic associations with premature mortality. Current diabetes guidelines in the UK recommend annual urinary albumin and serum creatinine determinations to screen for diabetic kidney disease. The aim of this study was to estimate the burden of CKD in patients with diabetes and examine the ability of serum creatinine and albuminuria to detect clinically meaningful CKD compared with estimated glomerular filtration rate (eGFR). Methods: All adults known to have diabetes in primary and secondary care in Salford, UK, alive with independent renal function on 1 January 2004 were included in this observational study (n = 7596). Demographic and laboratory parameters were obtained from the Electronic Patient Record. eGFR was determined using the 4-variable modification of diet in renal disease (MDRD) formula. Clinically meaningful CKD was defined as an eGFR

Original language	English
Pages (from-to)	88-92
Number of pages	4
Journal	Nephrology, Dialysis, Transplantation
Volume	21
Issue number	1
DOIs	https://doi.org/10.1093/ndt/gfi163
Publication status	Published - Jan 2006

Keywords

Diabetic kidney disease
Estimated glomerular filtration rate
Modification of diet in renal disease (MDRD) study equation
Sensitivity
Serum creatinine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1093/ndt/gfi163

Cite this

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title = "The unrecognized prevalence of chronic kidney disease in diabetes",

abstract = "Background: Diabetes mellitus and chronic kidney disease (CKD) are common and exhibit synergistic associations with premature mortality. Current diabetes guidelines in the UK recommend annual urinary albumin and serum creatinine determinations to screen for diabetic kidney disease. The aim of this study was to estimate the burden of CKD in patients with diabetes and examine the ability of serum creatinine and albuminuria to detect clinically meaningful CKD compared with estimated glomerular filtration rate (eGFR). Methods: All adults known to have diabetes in primary and secondary care in Salford, UK, alive with independent renal function on 1 January 2004 were included in this observational study (n = 7596). Demographic and laboratory parameters were obtained from the Electronic Patient Record. eGFR was determined using the 4-variable modification of diet in renal disease (MDRD) formula. Clinically meaningful CKD was defined as an eGFR",

keywords = "Diabetic kidney disease, Estimated glomerular filtration rate, Modification of diet in renal disease (MDRD) study equation, Sensitivity, Serum creatinine",

author = "Middleton, {Rachel J.} and Foley, {Robert N.} and Janet Hegarty and Cheung, {Ching M.} and Patrick McElduff and Gibson, {J. Martin} and Kalra, {Philip A.} and O'Donoghue, {Donal J.} and New, {John P.}",

year = "2006",

month = jan,

doi = "10.1093/ndt/gfi163",

language = "English",

volume = "21",

pages = "88--92",

journal = "Nephrology, Dialysis, Transplantation",

issn = "0931-0509",

publisher = "Oxford University Press",

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TY - JOUR

T1 - The unrecognized prevalence of chronic kidney disease in diabetes

AU - Middleton, Rachel J.

AU - Foley, Robert N.

AU - Hegarty, Janet

AU - Cheung, Ching M.

AU - McElduff, Patrick

AU - Gibson, J. Martin

AU - Kalra, Philip A.

AU - O'Donoghue, Donal J.

AU - New, John P.

PY - 2006/1

Y1 - 2006/1

N2 - Background: Diabetes mellitus and chronic kidney disease (CKD) are common and exhibit synergistic associations with premature mortality. Current diabetes guidelines in the UK recommend annual urinary albumin and serum creatinine determinations to screen for diabetic kidney disease. The aim of this study was to estimate the burden of CKD in patients with diabetes and examine the ability of serum creatinine and albuminuria to detect clinically meaningful CKD compared with estimated glomerular filtration rate (eGFR). Methods: All adults known to have diabetes in primary and secondary care in Salford, UK, alive with independent renal function on 1 January 2004 were included in this observational study (n = 7596). Demographic and laboratory parameters were obtained from the Electronic Patient Record. eGFR was determined using the 4-variable modification of diet in renal disease (MDRD) formula. Clinically meaningful CKD was defined as an eGFR

AB - Background: Diabetes mellitus and chronic kidney disease (CKD) are common and exhibit synergistic associations with premature mortality. Current diabetes guidelines in the UK recommend annual urinary albumin and serum creatinine determinations to screen for diabetic kidney disease. The aim of this study was to estimate the burden of CKD in patients with diabetes and examine the ability of serum creatinine and albuminuria to detect clinically meaningful CKD compared with estimated glomerular filtration rate (eGFR). Methods: All adults known to have diabetes in primary and secondary care in Salford, UK, alive with independent renal function on 1 January 2004 were included in this observational study (n = 7596). Demographic and laboratory parameters were obtained from the Electronic Patient Record. eGFR was determined using the 4-variable modification of diet in renal disease (MDRD) formula. Clinically meaningful CKD was defined as an eGFR

KW - Diabetic kidney disease

KW - Estimated glomerular filtration rate

KW - Modification of diet in renal disease (MDRD) study equation

KW - Sensitivity

KW - Serum creatinine

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DO - 10.1093/ndt/gfi163

M3 - Article

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SN - 0931-0509

VL - 21

SP - 88

EP - 92

JO - Nephrology, Dialysis, Transplantation

JF - Nephrology, Dialysis, Transplantation

IS - 1

ER -

The unrecognized prevalence of chronic kidney disease in diabetes

Abstract

Keywords

UN SDGs

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