The Use of Raman Tweezers and Chemometric Analysis to Discriminate the Urological Cell Lines, PC-3, LNCaP, BPH and MGH-U1

Timothy Harvey; C Hughes; Andrew D. Ward; E Gazi; Elsa Correia Faria; N Clarke; MD Brown; Richard D. Snook; Peter Gardner; Elsa Correia Faria - bill; V. K. Vaidyan; V. S. Jayakumar

doi:10.1063/1.3046192

The Use of Raman Tweezers and Chemometric Analysis to Discriminate the Urological Cell Lines, PC-3, LNCaP, BPH and MGH-U1

Timothy Harvey, C Hughes, Andrew D. Ward, E Gazi, Elsa Correia Faria, N Clarke, MD Brown, Richard D. Snook, Peter Gardner, Elsa Correia Faria - bill, V. K. Vaidyan, V. S. Jayakumar

Research output: Chapter in Book/Conference proceeding › Conference contribution › peer-review

Abstract

Here we report on investigations into using Raman optical tweezers to analyse both live and chemically fixed prostate and bladder cells. Spectra were subjected to chemometric analysis to discriminate and classify the cell types based on their spectra. Subsequent results revealed the potential of Raman tweezers as a potential clinical diagnostic tool.

Original language	English
Title of host publication	American Institute of Physics
Editors	V K Vaidyan, V S Jayakumar, Dept Sci Dev Org, Council Sci Technol, Dept Biotechnol Kerala State Indust Res, Technol Council Sci, Indian Bank Camo Environm
Publisher	American Institute of Physics
Pages	138-140
Number of pages	3
Volume	1075
ISBN (Print)	0094-243X 978-0-7354-0606-3
DOIs	https://doi.org/10.1063/1.3046192
Publication status	Published - 14 Nov 2008
Event	2nd International Conference on Perspectives in Vibrational Spectroscopy - Thiruvananthapuram, INDIA Duration: 24 Feb 2008 → 28 Feb 2008

Conference

Conference	2nd International Conference on Perspectives in Vibrational Spectroscopy
City	Thiruvananthapuram, INDIA
Period	24/02/08 → 28/02/08

Keywords

Raman tweezers
prostate cancer
vibrational spectroscopy
chemometrics
Physics, Multidisciplinary

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10.1063/1.3046192

Cite this

Harvey, T., Hughes, C., Ward, A. D., Gazi, E., Faria, E. C., Clarke, N., Brown, MD., Snook, R. D., Gardner, P., Correia Faria - bill, E., Vaidyan, V. K., & Jayakumar, V. S. (2008). The Use of Raman Tweezers and Chemometric Analysis to Discriminate the Urological Cell Lines, PC-3, LNCaP, BPH and MGH-U1. In V. K. Vaidyan, V. S. Jayakumar, D. S. Dev Org, C. S. Technol, D. B. K. S. Indust Res, T. Council Sci, & I. B. C. Environm (Eds.), American Institute of Physics (Vol. 1075, pp. 138-140). American Institute of Physics. https://doi.org/10.1063/1.3046192

Harvey, Timothy ; Hughes, C ; Ward, Andrew D. et al. / The Use of Raman Tweezers and Chemometric Analysis to Discriminate the Urological Cell Lines, PC-3, LNCaP, BPH and MGH-U1. American Institute of Physics. editor / V K Vaidyan ; V S Jayakumar ; Dept Sci Dev Org ; Council Sci Technol ; Dept Biotechnol Kerala State Indust Res ; Technol Council Sci ; Indian Bank Camo Environm. Vol. 1075 American Institute of Physics, 2008. pp. 138-140

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title = "The Use of Raman Tweezers and Chemometric Analysis to Discriminate the Urological Cell Lines, PC-3, LNCaP, BPH and MGH-U1",

abstract = "Here we report on investigations into using Raman optical tweezers to analyse both live and chemically fixed prostate and bladder cells. Spectra were subjected to chemometric analysis to discriminate and classify the cell types based on their spectra. Subsequent results revealed the potential of Raman tweezers as a potential clinical diagnostic tool.",

keywords = "Raman tweezers, prostate cancer, vibrational spectroscopy, chemometrics, Physics, Multidisciplinary",

author = "Timothy Harvey and C Hughes and Ward, \{Andrew D.\} and E Gazi and Faria, \{Elsa Correia\} and N Clarke and MD Brown and Snook, \{Richard D.\} and Peter Gardner and \{Correia Faria - bill\}, Elsa and Vaidyan, \{V. K.\} and Jayakumar, \{V. S.\}",

note = "Indian Space Res Org, Dept Space Defense Res Harvey, T. J. Hughes, C. Ward, A. D. Gazi, E. Faria, E. Correia Clarke, N. W. Brown, M. Snook, R. Gardner, P. 10 MELVILLE BIS05; 2nd International Conference on Perspectives in Vibrational Spectroscopy ; Conference date: 24-02-2008 Through 28-02-2008",

year = "2008",

month = nov,

day = "14",

doi = "10.1063/1.3046192",

language = "English",

isbn = "0094-243X 978-0-7354-0606-3",

volume = "1075",

pages = "138--140",

editor = "Vaidyan, \{V K\} and Jayakumar, \{V S\} and \{Dev Org\}, \{Dept Sci\} and Technol, \{Council Sci\} and \{Indust Res\}, \{Dept Biotechnol Kerala State\} and \{Council Sci\}, Technol and Environm, \{Indian Bank Camo\}",

booktitle = "American Institute of Physics",

publisher = "American Institute of Physics",

address = "United States",

}

Harvey, T, Hughes, C, Ward, AD, Gazi, E, Faria, EC, Clarke, N, Brown, MD, Snook, RD, Gardner, P, Correia Faria - bill, E, Vaidyan, VK & Jayakumar, VS 2008, The Use of Raman Tweezers and Chemometric Analysis to Discriminate the Urological Cell Lines, PC-3, LNCaP, BPH and MGH-U1. in VK Vaidyan, VS Jayakumar, DS Dev Org, CS Technol, DBKS Indust Res, T Council Sci & IBC Environm (eds), American Institute of Physics. vol. 1075, American Institute of Physics, pp. 138-140, 2nd International Conference on Perspectives in Vibrational Spectroscopy, Thiruvananthapuram, INDIA, 24/02/08. https://doi.org/10.1063/1.3046192

The Use of Raman Tweezers and Chemometric Analysis to Discriminate the Urological Cell Lines, PC-3, LNCaP, BPH and MGH-U1. / Harvey, Timothy; Hughes, C; Ward, Andrew D. et al.
American Institute of Physics. ed. / V K Vaidyan; V S Jayakumar; Dept Sci Dev Org; Council Sci Technol; Dept Biotechnol Kerala State Indust Res; Technol Council Sci; Indian Bank Camo Environm. Vol. 1075 American Institute of Physics, 2008. p. 138-140.

Research output: Chapter in Book/Conference proceeding › Conference contribution › peer-review

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T1 - The Use of Raman Tweezers and Chemometric Analysis to Discriminate the Urological Cell Lines, PC-3, LNCaP, BPH and MGH-U1

AU - Harvey, Timothy

AU - Hughes, C

AU - Ward, Andrew D.

AU - Gazi, E

AU - Faria, Elsa Correia

AU - Clarke, N

AU - Brown, MD

AU - Snook, Richard D.

AU - Gardner, Peter

AU - Correia Faria - bill, Elsa

AU - Vaidyan, V. K.

AU - Jayakumar, V. S.

N1 - Indian Space Res Org, Dept Space Defense Res Harvey, T. J. Hughes, C. Ward, A. D. Gazi, E. Faria, E. Correia Clarke, N. W. Brown, M. Snook, R. Gardner, P. 10 MELVILLE BIS05

PY - 2008/11/14

Y1 - 2008/11/14

N2 - Here we report on investigations into using Raman optical tweezers to analyse both live and chemically fixed prostate and bladder cells. Spectra were subjected to chemometric analysis to discriminate and classify the cell types based on their spectra. Subsequent results revealed the potential of Raman tweezers as a potential clinical diagnostic tool.

AB - Here we report on investigations into using Raman optical tweezers to analyse both live and chemically fixed prostate and bladder cells. Spectra were subjected to chemometric analysis to discriminate and classify the cell types based on their spectra. Subsequent results revealed the potential of Raman tweezers as a potential clinical diagnostic tool.

KW - Raman tweezers

KW - prostate cancer

KW - vibrational spectroscopy

KW - chemometrics

KW - Physics, Multidisciplinary

U2 - 10.1063/1.3046192

DO - 10.1063/1.3046192

M3 - Conference contribution

SN - 0094-243X 978-0-7354-0606-3

VL - 1075

SP - 138

EP - 140

BT - American Institute of Physics

A2 - Vaidyan, V K

A2 - Jayakumar, V S

A2 - Dev Org, Dept Sci

A2 - Technol, Council Sci

A2 - Indust Res, Dept Biotechnol Kerala State

A2 - Council Sci, Technol

A2 - Environm, Indian Bank Camo

PB - American Institute of Physics

T2 - 2nd International Conference on Perspectives in Vibrational Spectroscopy

Y2 - 24 February 2008 through 28 February 2008

ER -

Harvey T, Hughes C, Ward AD, Gazi E, Faria EC, Clarke N et al. The Use of Raman Tweezers and Chemometric Analysis to Discriminate the Urological Cell Lines, PC-3, LNCaP, BPH and MGH-U1. In Vaidyan VK, Jayakumar VS, Dev Org DS, Technol CS, Indust Res DBKS, Council Sci T, Environm IBC, editors, American Institute of Physics. Vol. 1075. American Institute of Physics. 2008. p. 138-140 doi: 10.1063/1.3046192

The Use of Raman Tweezers and Chemometric Analysis to Discriminate the Urological Cell Lines, PC-3, LNCaP, BPH and MGH-U1

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