Therapeutic drug monitoring (TDM) of antifungal agents: Guidelines from the british society for medical mycology

H. Ruth Ashbee, Rosemary A. Barnes, Elizabeth M. Johnson, Malcolm D. Richardson, Rebecca Gorton, William W. Hope

    Research output: Contribution to journalArticlepeer-review

    Abstract

    The burden of human disease related to medically important fungal pathogens is substantial. An improved understanding of antifungal pharmacology and antifungal pharmacokinetics-pharmacodynamics has resulted in therapeutic drug monitoring (TDM) becoming a valuable adjunct to the routine administration of some antifungal agents. TDM may increase the probability of a successful outcome, prevent drug-related toxicity and potentially prevent the emergence of antifungal drug resistance. Much of the evidence that supports TDM is circumstantial. This document reviews the available literature and provides a series of recommendations for TDM of antifungal agents.© The Author 2013. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy.All rights reserved.
    Original languageEnglish
    Article numberdkt508
    Pages (from-to)1162-1176
    Number of pages14
    JournalJournal of Antimicrobial Chemotherapy
    Volume69
    Issue number5
    DOIs
    Publication statusPublished - 2014

    Keywords

    • Fungal diseases
    • Fungal pathogens
    • Triazoles

    Fingerprint

    Dive into the research topics of 'Therapeutic drug monitoring (TDM) of antifungal agents: Guidelines from the british society for medical mycology'. Together they form a unique fingerprint.

    Cite this