Thermogenic capacity and brown adipose tissue activity in the common marmoset

Nancy J. Rothwell, Michael J. Stock

Research output: Contribution to journalArticlepeer-review

Abstract

1. 1. Resting oxygen consumption was measured in anaesthetized male and female common marmosets (Callithrix jacchus) at 29°C. 2. 2. Injection of noradrenaline caused a marked increase in oxygen consumption (63%), but this response was lower in males. Large deposits (750 mg) of brown adipose tissue (BAT) were dissected from the cervical, subscapular, axillary and perirenal areas. 3. 3. High levels of guanosine diphosphate binding to isolated brown fat mitochondria were observed, indicating that the thermogenic proton conductance pathway is very active in brown fat from the marmoset. 4. 4. High levels of brown adipose tissue thermogenesis in these animals may be related to a requirement for diet-induced thermogenesis. © 1985.
Original languageEnglish
Pages (from-to)683-686
Number of pages3
JournalComparative Biochemistry and Physiology. Part A: Molecular & Integrative Physiology
Volume81
Issue number3
Publication statusPublished - 1985

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