THREE HYBRID SCREENING ASSAY USING REVERSE TRANSFECTED MAMMALIAN CELL ARRAYS

James Freeth; Adam Stevens; David Cook, Ian

THREE HYBRID SCREENING ASSAY USING REVERSE TRANSFECTED MAMMALIAN CELL ARRAYS

James Freeth (Inventor), Adam Stevens (Inventor), David Cook, Ian (Inventor)

Division of Developmental Biology & Medicine (L5)

Research output: Patent

Abstract

Assay methods are provided for performing a three-hybrid assay in mammalian cells. Arrays for conducting the assay methods are also provided. The assays methods and arrays may be used to screen a DNA library to identify the target protein of a known small molecule, study target protein: small molecule interaction, or screen a library of small molecules against a known target protein.

Original language	English
Patent number	WO2007042771
IPC	G01N 33/ 68 A I
Priority date	10/10/05
Publication status	Published - 19 Apr 2007

Cite this

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title = "THREE HYBRID SCREENING ASSAY USING REVERSE TRANSFECTED MAMMALIAN CELL ARRAYS",

abstract = "Assay methods are provided for performing a three-hybrid assay in mammalian cells. Arrays for conducting the assay methods are also provided. The assays methods and arrays may be used to screen a DNA library to identify the target protein of a known small molecule, study target protein: small molecule interaction, or screen a library of small molecules against a known target protein.",

author = "James Freeth and Adam Stevens and {Cook, Ian}, David",

year = "2007",

month = apr,

day = "19",

language = "English",

type = "Patent",

note = "WO2007042771; G01N 33/ 68 A I",

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T1 - THREE HYBRID SCREENING ASSAY USING REVERSE TRANSFECTED MAMMALIAN CELL ARRAYS

AU - Freeth, James

AU - Stevens, Adam

AU - Cook, Ian, David

PY - 2007/4/19

Y1 - 2007/4/19

N2 - Assay methods are provided for performing a three-hybrid assay in mammalian cells. Arrays for conducting the assay methods are also provided. The assays methods and arrays may be used to screen a DNA library to identify the target protein of a known small molecule, study target protein: small molecule interaction, or screen a library of small molecules against a known target protein.

AB - Assay methods are provided for performing a three-hybrid assay in mammalian cells. Arrays for conducting the assay methods are also provided. The assays methods and arrays may be used to screen a DNA library to identify the target protein of a known small molecule, study target protein: small molecule interaction, or screen a library of small molecules against a known target protein.

M3 - Patent

M1 - WO2007042771

ER -

THREE HYBRID SCREENING ASSAY USING REVERSE TRANSFECTED MAMMALIAN CELL ARRAYS

Abstract

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