Three-way assessment of long-chain n-3 PUFA nutrition: By questionnaire and matched blood and skin samples

Sarah C. Wallingford; Suzanne M. Pilkington; Karen A. Massey; Naser M I Al-Aasswad; Torukiri I. Ibiebele; Maria Celia Hughes; Susan Bennett; Anna Nicolaou; Lesley E. Rhodes; Adèle C. Green

doi:10.1017/S0007114512001997

Three-way assessment of long-chain n-3 PUFA nutrition: By questionnaire and matched blood and skin samples

Sarah C. Wallingford, Suzanne M. Pilkington, Karen A. Massey, Naser M I Al-Aasswad, Torukiri I. Ibiebele, Maria Celia Hughes, Susan Bennett, Anna Nicolaou, Lesley E. Rhodes, Adèle C. Green

Cancer Research UK Manchester Institute

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Abstract

The long-chain n-3 PUFA, EPA, is believed to be important for skin health, including roles in the modulation of inflammation and protection from photodamage. FFQ and blood levels are used as non-invasive proxies for assessing skin PUFA levels, but studies examining how well these proxies reflect target organ content are lacking. In seventy-eight healthy women (mean age 42·8, range 21-60 years) residing in Greater Manchester, we performed a quantitative analysis of long-chain n-3 PUFA nutrition estimated from a self-reported FFQ (n 75) and correlated this with n-3 PUFA concentrations in erythrocytes (n 72) and dermis (n 39). Linear associations between the three n-3 PUFA measurements were assessed by Spearman correlation coefficients and agreement between these measurements was estimated. Average total dietary content of the principal long-chain n-3 PUFA EPA and DHA was 171 (sd 168) and 236 (sd 248)Â mg/d, respectively. EPA showed significant correlations between FFQ assessments and both erythrocyte (r 0·57, P

Original language	English
Pages (from-to)	701-708
Number of pages	7
Journal	British Journal of Nutrition
Volume	109
Issue number	4
DOIs	https://doi.org/10.1017/S0007114512001997 https://doi.org/10.1017/S0007114512001997
Publication status	Published - 28 Feb 2013

Keywords

Correlations
Erythrocytes
FFQ
n-3 PUFA
Skin

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Wallingford, S. C., Pilkington, S. M., Massey, K. A., Al-Aasswad, N. M. I., Ibiebele, T. I., Celia Hughes, M., Bennett, S., Nicolaou, A., Rhodes, L. E., & Green, A. C. (2013). Three-way assessment of long-chain n-3 PUFA nutrition: By questionnaire and matched blood and skin samples. British Journal of Nutrition, 109(4), 701-708. https://doi.org/10.1017/S0007114512001997, https://doi.org/10.1017/S0007114512001997

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Wallingford, SC, Pilkington, SM, Massey, KA, Al-Aasswad, NMI, Ibiebele, TI, Celia Hughes, M, Bennett, S, Nicolaou, A, Rhodes, LE & Green, AC 2013, 'Three-way assessment of long-chain n-3 PUFA nutrition: By questionnaire and matched blood and skin samples', British Journal of Nutrition, vol. 109, no. 4, pp. 701-708. https://doi.org/10.1017/S0007114512001997, https://doi.org/10.1017/S0007114512001997

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AU - Wallingford, Sarah C.

AU - Pilkington, Suzanne M.

AU - Massey, Karen A.

AU - Al-Aasswad, Naser M I

AU - Ibiebele, Torukiri I.

AU - Celia Hughes, Maria

AU - Bennett, Susan

AU - Nicolaou, Anna

AU - Rhodes, Lesley E.

AU - Green, Adèle C.

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DO - 10.1017/S0007114512001997

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JO - British Journal of Nutrition

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ER -

Three-way assessment of long-chain n-3 PUFA nutrition: By questionnaire and matched blood and skin samples

Abstract

Keywords

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