Tight control in the treatment of rheumatoid arthritis: Efficacy and feasibility

M. F. Bakker, J. W G Jacobs, S. M M Verstappen, J. W J Bijlsma

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Objective: To evaluate the available evidence on the efficacy and feasibility of the new concept of tight control in randomised trials in patients with rheumatoid arthritis (RA). Tight control is a treatment strategy tailored to the individual patient with RA, which aims to achieve a predefined level of low disease activity or remission within a certain period of time. Methods: The literature database PubMed was searched and yielded four trials: the FIN-RACo trial, the TICORA study, the BeSt study and the CAMERA study. Results: Tight control resulted in greater improvement and a higher percentage of patients meeting the preset aim of low disease activity or remission when compared to the control intervention. In the FIN-RACo trial, aimed at DAS28
    Original languageEnglish
    Pages (from-to)56-60
    Number of pages4
    JournalAnnals of the rheumatic diseases
    Volume66
    Issue number3
    DOIs
    Publication statusPublished - Nov 2007

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