Tooth loss and osteoporosis: The osteodent study

Kety Nicopoulou-Karayianni, Panagiotis Tzoutzoukos, Anastasia Mitsea, Athanasios Karayiannis, Kostas Tsiklakis, Reinhilde Jacobs, Christina Lindh, Paul Van Der Stelt, Philip Allen, Jim Graham, Keith Horner, Hugh Devlin, Susan Pavitt, Jingsong Yuan

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    Nicopoulou-Karayianni K, Tzoutzoukos P, Mitsea A, Karayiannis A, Tsiklakis K, Jacobs R, Lindh C, van der Stelt P, Allen P, Graham J, Horner K, Devlin H, Pavitt S, Yuan J. Tooth loss and osteoporosis: the osteodent study. J Clin Periodontol 2009; 36: 190-197. doi: 10.1111/j.1600-051X.2008.01365. Abstract Aim: To determine the cross-sectional association of the osteoporotic status of patients with the number of their teeth, with and without taking into account age and/or smoking. Material & Methods: At four centres, the study recruited 665 females aged 45-70 years and the number of teeth was counted for 651 subjects. Bone density was measured at the total hip, femoral neck and lumbar spine. Results: The mean number of teeth in the osteoporotic subjects was 3.3 fewer than normal subjects and 2.1 fewer if those with no teeth were excluded. The association between osteoporosis and having 0, three clusters were identified corresponding to different degrees of tooth loss. The overall effect of osteoporosis was as follows: -1.8 teeth before and after adjusting for smoking, -1.2 teeth after adjusting for age, and -1.1 teeth after adjusting for both age and smoking. Conclusions: We have established a significant association between osteoporosis and tooth loss after adjusting the effect for age and smoking. © 2009 John Wiley & Sons A/S.
    Original languageEnglish
    Pages (from-to)190-197
    Number of pages7
    JournalJournal of Clinical Periodontology
    Issue number3
    Publication statusPublished - Mar 2009


    • Bone mineral density
    • Osteoporosis
    • Tooth loss


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