Total agenesis of the corpus callosum in a patient with childhood-onset schizophrenia

Jaime Eduardo Cecilio Hallak, José Alexandre De Sousa Crippa, Joel Porfírio Pinto, João Paulo Machado De Sousa, Clarissa Trzesniak, Serdar Murat Dursun, Phillip McGuire, John Francis William Deakin, Antonio Waldo Zuardi

    Research output: Contribution to journalArticlepeer-review

    Abstract

    The hypothesis that schizophrenia involves aberrant inter-hemispheric communication has a long pedigree, however its precise role remains unclear. We therefore report the case of a total agenesis of the corpus callosum in a 21-year-old man with childhood-onset schizophrenia. The presence of schizophrenia with very early onset on absence of corpus callosum offers an opportunity to examine neurodevelopmental model and theories regarding to interhemispheric communication in the pathogenesis of psychosis.
    Original languageEnglish
    Pages (from-to)1216-1219
    Number of pages3
    JournalArquivos de Neuro-Psiquiatria
    Volume65
    Issue number4 B
    DOIs
    Publication statusPublished - Dec 2007

    Keywords

    • Agenesis
    • Corpus callosum
    • Schizophrenia

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