Total cardiovascular risk approach to improve efficiency of cardiovascular prevention in resource constrain settings

Shanthi Mendis, Lars H. Lindholm, Simon G. Anderson, Ala Alwan, Rajendra Koju, Basden J C Onwubere, Azhar Mahmood Kayani, Nihal Abeysinghe, Alfredo Duneas, Sergo Tabagari, Wu Fan, Nizal Sarraf-Zadegan, Porfirio Nordet, Judith Whitworth, Anthony Heagerty

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Objectives: To determine the population distribution of cardiovascular risk in eight low- and middle-income countries and compare the cost of drug treatment based on cardiovascular risk (cardiovascular risk thresholds ≥30%/≥40%) with single risk factor cutoff levels. Study Design and Setting: Using World Health Organization (WHO) and the International Society of Hypertension risk prediction charts, cardiovascular risk was categorized in a cross-sectional study of 8,625 randomly selected people aged 40-80 years (mean age, 54.6 years) from defined geographic regions of Nigeria, Iran, China, Pakistan, Georgia, Nepal, Cuba, and Sri Lanka. Cost estimates for drug therapy were calculated for three countries. Results: A large fraction (90.0-98.9%) of the study population has a 10-year cardiovascular risk
    Original languageEnglish
    Pages (from-to)1451-1462
    Number of pages11
    JournalJournal of Clinical Epidemiology
    Volume64
    Issue number12
    DOIs
    Publication statusPublished - Dec 2011

    Keywords

    • Atherosclerosis
    • Cost saving
    • Health policy
    • Hypertension
    • Preventive cardiology
    • Risk

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