Total synthesis of a cuticular hydrocarbon from the cane beetle Antitrogus parvulus: Confirmation of the relative stereochemistry

Norazah B. Basar, Hao Liu, Devendra Negi, Hasnah M. Sirat, Gareth A. Morris, Eric J. Thomas

    Research output: Contribution to journalArticlepeer-review

    Abstract

    The stereoselective reaction of an allyl bromide with an aldehyde mediated by a low valency bismuth species was the key reaction in stereoselective syntheses of (4S,6R,8R,10S,16S)- and (4S,6R,8R,10S,16R)-4,6,8,10,16- pentamethyldocosanes. 13C NMR data for these compounds confirmed that the cuticular hydrocarbon isolated from the cane beetle Antitrogus parvulus was the (4S,6R,8R,10S,16S)-stereoisomer. © 2012 The Royal Society of Chemistry.
    Original languageEnglish
    Pages (from-to)1743-1745
    Number of pages2
    JournalOrganic and Biomolecular Chemistry
    Volume10
    Issue number9
    DOIs
    Publication statusPublished - 7 Mar 2012

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