Towards quantitatively reproducible substrates for SERS

Roger M. Jarvis, Helen E. Johnson, Emma Olembe, Arunkumar Panneerselvam, Mohammad A. Malik, Mohammad Afzaal, Paul O'Brien, Royston Goodacre

    Research output: Contribution to journalArticlepeer-review

    Abstract

    There is a need for a method to facilitate the development of novel, reproducible colloidal surface-enhanced Raman scattering (SERS) substrates to encourage the use of SERS in applied studies. In this study we show for the first time that by using suitably designed SERS experiments in conjunction with multivariate analysis of variance (MANOVA), an objective assessment of colloidal SERS reproducibility can be made. This is demonstrated with the analyte cresyl violet, but could be extended to any analyte of interest for which reproducible SERS data are needed. © The Royal Society of Chemistry.
    Original languageEnglish
    Pages (from-to)1449-1452
    Number of pages3
    JournalAnalyst
    Volume133
    Issue number10
    DOIs
    Publication statusPublished - 2008

    Keywords

    • SURFACE-ENHANCED RAMAN
    • SILVER NANOPARTICLES
    • SCATTERING
    • GOLD
    • VARIANCE
    • MANOVA
    • MODEL
    • DYES

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