Toxicity of Ocimum sanctum L. essential oil to Aedes aegypti Larvae and its chemical composition

A. A. Gbolade, G. B. Lockwood

    Research output: Contribution to journalArticlepeer-review

    Abstract

    The herb essential oil of Ocimum sanctum from Nigeria was investigated for mosquito larvicidal activity and its composition studied by gas chromatography and gas chromatography-mass spectrometry for the first time. A good larvicidal action (LD50 85.11 ppm) against fourth instar Aedes aegypti mosquitoes which was far less than that of a positive control, endosulphan (LC50, 0.96 ppm) was observed for the oil. Seventeen components representing 88.4 % of total oil were fully identified. Oxygenated monoterpenes (51.1 %) and sesquiterpene hydrocarbons (27.5 %) formed the main chemical groups in the oil. The major constituents of the oil were methyleugenol (44.7 %) and isocaryophyllene (16.8 %), which categorise the oil into a different chemical variety.
    Original languageEnglish
    Pages (from-to)148-153
    Number of pages5
    JournalJournal of Essential Oil-Bearing Plants
    Volume11
    Issue number2
    Publication statusPublished - Mar 2008

    Keywords

    • Aedes aegypti
    • Essential oil
    • Isocaryophyllene
    • Larval toxicity
    • Methyleugenol
    • Ocimum sanctum

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