Transformation of a hydroxyl into an acyl group on α-pyrone ring: A novel route to 3,4-diacylcoumarins

Antigoni Kotali, Despina A. Nasiopoulou, Philip A. Harris, Madeleine Helliwell, John A. Joule

    Research output: Contribution to journalArticlepeer-review

    Abstract

    The transformation of a hydroxyl into an acyl group, a transformation which has been extensively investigated on the benzene nucleus of several substrates, is now applied successfully for the first time to a heterocyclic ring and specifically to the pyrone ring of coumarin to yield novel 3,4-diacylcoumarins in good yields. The reaction involves formation of a new C-C bond.

    Original languageEnglish
    Pages (from-to)761-766
    Number of pages6
    JournalTetrahedron
    Volume68
    Issue number2
    DOIs
    Publication statusPublished - 14 Jan 2012

    Keywords

    • 3,4-Diacylcoumarins
    • 4-Hydroxycoumarin
    • Acylhydrazones
    • C-C bond formation
    • Diacetoxyiodoso benzene
    • Lead tetraacetate

    Fingerprint

    Dive into the research topics of 'Transformation of a hydroxyl into an acyl group on α-pyrone ring: A novel route to 3,4-diacylcoumarins'. Together they form a unique fingerprint.

    Cite this