Transverse-tubule remodelling in remote and border regions following myocardial infarction

Tharushi Perera; Christian Pinali; Emma Radcliffe; Barbara Niort; Charlene Pius; Andrew Trafford

doi:10.22443/rms.mmc2021.53

Transverse-tubule remodelling in remote and border regions following myocardial infarction

Tharushi Perera, Christian Pinali, Emma Radcliffe, Barbara Niort, Charlene Pius, Andrew Trafford

Division of Cardiovascular Sciences (L5)

Research output: Contribution to conference › Abstract › peer-review

Abstract

Serial block face scanning electron microscopy (SBF-SEM) was used to image ventricular cardiac myocytes in healthy and myocardial infarction (MI) sheep. 3-dimensional renderings of EM stacks of images revealed an increase of t-tubule remodelling following myocardial infarction, from the remote myocardium to the peri-infarct border zone. This study, thereby increases our understanding of the cardiac ultrastructural remodelling following MI.

Original language	English
DOIs	https://doi.org/10.22443/rms.mmc2021.53
Publication status	Published - 20 Aug 2021
Event	Microscience Microscopy Congress 2021 - Duration: 6 Jul 2021 → 8 Jul 2021

Conference

Conference	Microscience Microscopy Congress 2021
Period	6/07/21 → 8/07/21

Keywords

serial block face scanning electron microscopy
transverse-tubule remodelling
myocardial infarction
fragmentation

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10.22443/rms.mmc2021.53

Cite this

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title = "Transverse-tubule remodelling in remote and border regions following myocardial infarction",

abstract = "Serial block face scanning electron microscopy (SBF-SEM) was used to image ventricular cardiac myocytes in healthy and myocardial infarction (MI) sheep. 3-dimensional renderings of EM stacks of images revealed an increase of t-tubule remodelling following myocardial infarction, from the remote myocardium to the peri-infarct border zone. This study, thereby increases our understanding of the cardiac ultrastructural remodelling following MI. ",

keywords = "serial block face scanning electron microscopy, transverse-tubule remodelling, myocardial infarction, fragmentation",

author = "Tharushi Perera and Christian Pinali and Emma Radcliffe and Barbara Niort and Charlene Pius and Andrew Trafford",

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doi = "10.22443/rms.mmc2021.53",

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T1 - Transverse-tubule remodelling in remote and border regions following myocardial infarction

AU - Perera, Tharushi

AU - Pinali, Christian

AU - Radcliffe, Emma

AU - Niort, Barbara

AU - Pius, Charlene

AU - Trafford, Andrew

PY - 2021/8/20

Y1 - 2021/8/20

N2 - Serial block face scanning electron microscopy (SBF-SEM) was used to image ventricular cardiac myocytes in healthy and myocardial infarction (MI) sheep. 3-dimensional renderings of EM stacks of images revealed an increase of t-tubule remodelling following myocardial infarction, from the remote myocardium to the peri-infarct border zone. This study, thereby increases our understanding of the cardiac ultrastructural remodelling following MI.

AB - Serial block face scanning electron microscopy (SBF-SEM) was used to image ventricular cardiac myocytes in healthy and myocardial infarction (MI) sheep. 3-dimensional renderings of EM stacks of images revealed an increase of t-tubule remodelling following myocardial infarction, from the remote myocardium to the peri-infarct border zone. This study, thereby increases our understanding of the cardiac ultrastructural remodelling following MI.

KW - serial block face scanning electron microscopy

KW - transverse-tubule remodelling

KW - myocardial infarction

KW - fragmentation

UR - https://www.mendeley.com/catalogue/89b040f5-cbca-3f35-b358-04a30ab1358e/

U2 - 10.22443/rms.mmc2021.53

DO - 10.22443/rms.mmc2021.53

M3 - Abstract

T2 - Microscience Microscopy Congress 2021

Y2 - 6 July 2021 through 8 July 2021

ER -

Transverse-tubule remodelling in remote and border regions following myocardial infarction

Abstract

Conference

Keywords

Access to Document

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