Trends in admission prevalence, illness severity and survival of haematological patients treated in Dutch intensive care units

Maarten Van Vliet, Ilona W M Verburg, Mark Van Den Boogaard, Nicolette F. De Keizer, Niels Peek, Nicole M A Blijlevens, Peter Pickkers

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Purpose: To explore trends over time in admission prevalence and (risk-adjusted) mortality of critically ill haematological patients and compare these trends to those of several subgroups of patients admitted to the medical intensive care unit (medical ICU patients). Methods: A total of 1,741 haematological and 60,954 non-haematological patients admitted to the medical ICU were analysed. Trends over time and differences between two subgroups of haematological medical ICU patients and four subgroups of non-haematological medical ICU patients were assessed, as well as the influence of leukocytopenia. Results: The proportion of haematological patients among all medical ICU patients increased over time [odds ratio (OR) 1.06; 95 % confidence interval (CI) 1.03-1.10 per year; p <0.001]. Risk-adjusted mortality was significantly higher for haematological patients admitted to the ICU with white blood cell (WBC) counts of
    Original languageEnglish
    Pages (from-to)1275-1284
    Number of pages9
    JournalIntensive care medicine
    Volume40
    Issue number9
    DOIs
    Publication statusPublished - 28 Jun 2014

    Keywords

    • Haematological malignancy
    • ICU outcome
    • Illness severity
    • Prospective intensive care evaluation

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