Tris-ureas as transmembrane anion transporters

Martina Olivari, Riccardo Montis, Stuart N. Berry, Louise E. Karagiannidis, Simon J. Coles, Peter N. Horton, Lucy K. Mapp, Philip A. Gale, Claudia Caltagirone

    Research output: Contribution to journalArticlepeer-review


    Nine tris-urea receptors (L1-L9) have been synthesised and shown to coordinate to a range of anionic guests both by 1H NMR titration techniques and single crystal X-ray structural analysis. The compounds have been shown to be capable of mediating the exchange of chloride and nitrate and also chloride and bicarbonate across POPC or POPC:cholesterol 7:3 vesicle bilayer membranes at low transporter loadings. An interesting dependency of anion transport on the nature of the cation is evidence to suggest that a M+/Cl- cotransport process may also contribute to the release of chloride from the vesicles.

    Original languageEnglish
    Pages (from-to)11892-11897
    Number of pages6
    JournalDalton Transactions
    Issue number29
    Publication statusPublished - 1 Jan 2016


    Dive into the research topics of 'Tris-ureas as transmembrane anion transporters'. Together they form a unique fingerprint.

    Cite this