Tropoelastin and Elastin Assembly

Jazmin  Ozsvar; Chengeng Yang; Stuart Cain; Clair Baldock; Anna  Tarakanova; Anthony S  Weiss

Tropoelastin and Elastin Assembly

Jazmin Ozsvar, Chengeng Yang, Stuart Cain, Clair Baldock, Anna Tarakanova, Anthony S Weiss

Division of Cell Matrix Biology & Regenerative Medicine (L5)

Research output: Contribution to journal › Article › peer-review

Abstract

Elastic fibers are an important component of the extracellular matrix, providing stretch, resilience and cell interactivity to a broad range of elastic tissues. Elastin makes up the majority of elastic fibers and is formed by the hierarchical assembly of its monomer, tropoelastin. Our understanding of key aspects of the assembly process have been unclear due to the intrinsic properties of elastin and tropoelastin that render them difficult to study. This review focuses on recent developments that have shaped our current knowledge of elastin assembly through understanding the relationship between tropoelastin’s structure and function.

Original language	English
Journal	Frontiers in Bioengineering and Biotechnology
Publication status	Accepted/In press - 8 Feb 2021

Embargoed Document

Revised Ozsvar et al
Accepted author manuscript, 992 KB
Embargo ends: 1/01/31

Cite this

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title = "Tropoelastin and Elastin Assembly",

abstract = "Elastic fibers are an important component of the extracellular matrix, providing stretch, resilience and cell interactivity to a broad range of elastic tissues. Elastin makes up the majority of elastic fibers and is formed by the hierarchical assembly of its monomer, tropoelastin. Our understanding of key aspects of the assembly process have been unclear due to the intrinsic properties of elastin and tropoelastin that render them difficult to study. This review focuses on recent developments that have shaped our current knowledge of elastin assembly through understanding the relationship between tropoelastin{\textquoteright}s structure and function.",

author = "Jazmin Ozsvar and Chengeng Yang and Stuart Cain and Clair Baldock and Anna Tarakanova and Weiss, {Anthony S}",

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language = "English",

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T1 - Tropoelastin and Elastin Assembly

AU - Ozsvar, Jazmin

AU - Yang, Chengeng

AU - Cain, Stuart

AU - Baldock, Clair

AU - Tarakanova, Anna

AU - Weiss, Anthony S

PY - 2021/2/8

Y1 - 2021/2/8

N2 - Elastic fibers are an important component of the extracellular matrix, providing stretch, resilience and cell interactivity to a broad range of elastic tissues. Elastin makes up the majority of elastic fibers and is formed by the hierarchical assembly of its monomer, tropoelastin. Our understanding of key aspects of the assembly process have been unclear due to the intrinsic properties of elastin and tropoelastin that render them difficult to study. This review focuses on recent developments that have shaped our current knowledge of elastin assembly through understanding the relationship between tropoelastin’s structure and function.

AB - Elastic fibers are an important component of the extracellular matrix, providing stretch, resilience and cell interactivity to a broad range of elastic tissues. Elastin makes up the majority of elastic fibers and is formed by the hierarchical assembly of its monomer, tropoelastin. Our understanding of key aspects of the assembly process have been unclear due to the intrinsic properties of elastin and tropoelastin that render them difficult to study. This review focuses on recent developments that have shaped our current knowledge of elastin assembly through understanding the relationship between tropoelastin’s structure and function.

M3 - Article

SN - 2296-4185

JO - Frontiers in Bioengineering and Biotechnology

JF - Frontiers in Bioengineering and Biotechnology

ER -

Tropoelastin and Elastin Assembly

Abstract

Embargoed Document

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