Two new genes involved in signalling ambient pH in Aspergillus nidulans

H. N. Arst, E. Bignell, J. Tilburn

    Research output: Contribution to journalArticlepeer-review


    Two new genes, palH and palI, where mutations mimic the effects of acidic growth pH have been identified in Aspergillus nidulans. A palH mutation is phenotypically indistinguishable from mutations in the palA, palB, palC, and palF genes, whereas pall mutations differ only in that they allow some growth at pH 8. Mutations in palA, B, C, F, and H are epistatic to a palI mutation and the significance of this epistasis is discussed. Additionally, palE and palB mutations have been shown to be allelic. Thus, a total of six genes where mutations mimic acidic growth conditions has been identified.
    Original languageEnglish
    Pages (from-to)787-790
    Number of pages3
    JournalMolecular and General Genetics
    Issue number6
    Publication statusPublished - 1994


    • Acidity-mimicking mutations
    • Aspergillus nidulans
    • pH regulation


    Dive into the research topics of 'Two new genes involved in signalling ambient pH in Aspergillus nidulans'. Together they form a unique fingerprint.

    Cite this