Ultra-selective 1D clean in-phase correlation spectroscopy

Daniel A. Taylor; Peter Kiraly; Paul Bowyer; Mathias Nilsson; Laura Castanar; Gareth A. Morris; Ralph A. Adams

doi:10.1039/D3CC01333B

Ultra-selective 1D clean in-phase correlation spectroscopy

Daniel A. Taylor, Peter Kiraly, Paul Bowyer, Mathias Nilsson, Laura Castanar , Gareth A. Morris, Ralph A. Adams

Research output: Contribution to journal › Article › peer-review

Abstract

Selective 1D COSY can unambiguously identify coupled spins but is often limited both by lack of selectivity, and by unfavourable multiplet lineshapes. Here, ultra selective GEMSTONE excitation is employed with CLIP COSY to provide through-bond correlations for nuclei whose NMR signals overlap. The new method is illustrated using the coccidiostat lasalocid and the immunosuppressant cyclosporin.

Original language	English
Pages (from-to)	6734-6737
Journal	Chemical Communications
Volume	59
Issue number	44
DOIs	https://doi.org/10.1039/D3CC01333B
Publication status	Published - 20 Apr 2023

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Ultra selective 1D clean in phase correlation spectroscopy - Publication Data
Adams, R. W. (Creator), Taylor, D. A. (Creator), Morris, G. A. (Creator), Nilsson, M. (Creator) & Castañar, L. (Creator), University of Manchester Figshare, 25 Apr 2023
DOI: 10.48420/21909600, https://figshare.manchester.ac.uk/articles/dataset/Ultra_selective_1D_clean_in_phase_correlation_spectroscopy_-_Publication_Data/21909600
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title = "Ultra-selective 1D clean in-phase correlation spectroscopy",

abstract = "Selective 1D COSY can unambiguously identify coupled spins but is often limited both by lack of selectivity, and by unfavourable multiplet lineshapes. Here, ultra selective GEMSTONE excitation is employed with CLIP COSY to provide through-bond correlations for nuclei whose NMR signals overlap. The new method is illustrated using the coccidiostat lasalocid and the immunosuppressant cyclosporin.",

author = "Taylor, {Daniel A.} and Peter Kiraly and Paul Bowyer and Mathias Nilsson and Laura Castanar and Morris, {Gareth A.} and Adams, {Ralph A.}",

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T1 - Ultra-selective 1D clean in-phase correlation spectroscopy

AU - Taylor, Daniel A.

AU - Kiraly, Peter

AU - Bowyer, Paul

AU - Nilsson, Mathias

AU - Castanar , Laura

AU - Morris, Gareth A.

AU - Adams, Ralph A.

PY - 2023/4/20

Y1 - 2023/4/20

N2 - Selective 1D COSY can unambiguously identify coupled spins but is often limited both by lack of selectivity, and by unfavourable multiplet lineshapes. Here, ultra selective GEMSTONE excitation is employed with CLIP COSY to provide through-bond correlations for nuclei whose NMR signals overlap. The new method is illustrated using the coccidiostat lasalocid and the immunosuppressant cyclosporin.

AB - Selective 1D COSY can unambiguously identify coupled spins but is often limited both by lack of selectivity, and by unfavourable multiplet lineshapes. Here, ultra selective GEMSTONE excitation is employed with CLIP COSY to provide through-bond correlations for nuclei whose NMR signals overlap. The new method is illustrated using the coccidiostat lasalocid and the immunosuppressant cyclosporin.

U2 - 10.1039/D3CC01333B

DO - 10.1039/D3CC01333B

M3 - Article

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VL - 59

SP - 6734

EP - 6737

JO - Chemical Communications

JF - Chemical Communications

IS - 44

ER -

Ultra-selective 1D clean in-phase correlation spectroscopy

Abstract

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Ultra selective 1D clean in phase correlation spectroscopy - Publication Data

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