Unique Case of Bilateral Exudative Retinal Detachment following Creatine Supplementation in a Patient with Autosomal Dominant Bestrophinopathy

Konstantinos Kopsidas; Hedayat Javidi; Simon P Kelly; Tariq Aslam; Graeme Black; Sajjad Mahmood

doi:10.1159/000503853

Unique Case of Bilateral Exudative Retinal Detachment following Creatine Supplementation in a Patient with Autosomal Dominant Bestrophinopathy

Konstantinos Kopsidas, Hedayat Javidi, Simon P Kelly, Tariq Aslam, Graeme Black, Sajjad Mahmood

Royal Bolton Hospital NHS Foundation Trust

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Abstract

We report a case of bilateral serous retinal detachment in a patient with rod-cone dystrophy caused by mutation of BEST1. This followed creatine monohydrate use as a dietary supplement. A 39-year-old male with rod-cone dystrophy and low hyperopia developed extensive bilateral exudative retinal detachment following creatine monohydrate diet supplementation. Five days after stopping creatine use, the bilateral retinal detachments resolved completely. This may indicate a causative relation of creatine supplementation to development of serous retinal detachment in a susceptible patient with pre-existing retinal dystrophy.

Original language	English
Pages (from-to)	374-378
Number of pages	5
Journal	Case Reports in Ophthalmology
Volume	10
Issue number	3
DOIs	https://doi.org/10.1159/000503853
Publication status	Published - 26 Nov 2019

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503853Final published version, 434 KBLicence: CC BY-NC

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title = "Unique Case of Bilateral Exudative Retinal Detachment following Creatine Supplementation in a Patient with Autosomal Dominant Bestrophinopathy",

abstract = "We report a case of bilateral serous retinal detachment in a patient with rod-cone dystrophy caused by mutation of BEST1. This followed creatine monohydrate use as a dietary supplement. A 39-year-old male with rod-cone dystrophy and low hyperopia developed extensive bilateral exudative retinal detachment following creatine monohydrate diet supplementation. Five days after stopping creatine use, the bilateral retinal detachments resolved completely. This may indicate a causative relation of creatine supplementation to development of serous retinal detachment in a susceptible patient with pre-existing retinal dystrophy.",

author = "Konstantinos Kopsidas and Hedayat Javidi and Kelly, {Simon P} and Tariq Aslam and Graeme Black and Sajjad Mahmood",

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AU - Black, Graeme

AU - Mahmood, Sajjad

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AB - We report a case of bilateral serous retinal detachment in a patient with rod-cone dystrophy caused by mutation of BEST1. This followed creatine monohydrate use as a dietary supplement. A 39-year-old male with rod-cone dystrophy and low hyperopia developed extensive bilateral exudative retinal detachment following creatine monohydrate diet supplementation. Five days after stopping creatine use, the bilateral retinal detachments resolved completely. This may indicate a causative relation of creatine supplementation to development of serous retinal detachment in a susceptible patient with pre-existing retinal dystrophy.

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Unique Case of Bilateral Exudative Retinal Detachment following Creatine Supplementation in a Patient with Autosomal Dominant Bestrophinopathy

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